8QFD
| UFL1 E3 ligase bound 60S ribosome | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Makhlouf, L, Kulathu, Y, Zeqiraj, E. | 登録日 | 2023-09-04 | 公開日 | 2024-02-21 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons. Nature, 627, 2024
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8TXX
| Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A K15 in complex with RNF168 (Class 3) | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | 登録日 | 2023-08-24 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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8TXV
| Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A K15 in complex with RNF168 (Class 1) | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | 登録日 | 2023-08-24 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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8TXW
| Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A K15 in complex with RNF168 (Class 2) | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | 登録日 | 2023-08-24 | 公開日 | 2024-01-17 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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8Q87
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8Q7Z
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8Q7R
| Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB-Sil1 peptide | 分子名称: | 5-azanyl-1-oxidanyl-pentan-2-one, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | 著者 | Liwocha, J, Prabu, J.R, Kleiger, G, Schulman, B.A. | 登録日 | 2023-08-16 | 公開日 | 2024-02-21 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | 主引用文献 | Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting. Mol.Cell, 84, 2024
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8Q7H
| Structure of CUL9-RBX1 ubiquitin E3 ligase complex in unneddylated and neddylated conformation - focused cullin dimer | 分子名称: | Cullin-9, E3 ubiquitin-protein ligase RBX1, NEDD8, ... | 著者 | Hopf, L.V.M, Horn-Ghetko, D, Schulman, B.A. | 登録日 | 2023-08-16 | 公開日 | 2024-04-17 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex. Nat.Struct.Mol.Biol., 31, 2024
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8Q7N
| cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region) | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, MINX pre-mRNA, Microfibrillar-associated protein 1, ... | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Urlaub, H, Stark, H, Luehrmann, R. | 登録日 | 2023-08-16 | 公開日 | 2024-01-24 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM analyses of dimerized spliceosomes provide new insights into the functions of B complex proteins. Embo J., 43, 2024
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8TPU
| Subtomogram averaged consensus structure of the malarial 80S ribosome in Plasmodium falciparum-infected human erythrocytes | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Anton, L, Cheng, W, Zhu, X, Ho, C.M. | 登録日 | 2023-08-05 | 公開日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Divergent translational landscape reflects adaptation to biased codon usage in malaria parasites To Be Published
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8K82
| Cryo-EM structure of the yeast 80S ribosome with tigecycline, Not5 and P-site tRNA | 分子名称: | 18S rRNA, 23S rRNA, 40S ribosomal protein S1-A, ... | 著者 | Buschauer, R, Beckmann, R, Cheng, J. | 登録日 | 2023-07-28 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8Q00
| TssM-Ub-PA complex - A USP-like DUB from B. pseudomallei (193-430) reacted with Ub-PA | 分子名称: | 1,2-ETHANEDIOL, CITRATE ANION, Polyubiquitin-B, ... | 著者 | Uthoff, M, Hermanns, T, Hofmann, K, Baumann, U. | 登録日 | 2023-07-27 | 公開日 | 2023-12-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | The structural basis for deubiquitination by the fingerless USP-type effector TssM. Life Sci Alliance, 7, 2024
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8K2D
| Cryo-EM structure of the yeast 80S ribosome with tigecycline, eEF2, Stm1 and eIF5A | 分子名称: | 18S rRNA, 23S rRNA, 40S ribosomal protein S1-A, ... | 著者 | Buschauer, R, Beckmann, R, Cheng, J. | 登録日 | 2023-07-12 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8K2C
| Cryo-EM structure of the human 80S ribosome with Tigecycline | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | 著者 | Li, X, Wang, M, Cheng, J. | 登録日 | 2023-07-12 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8PQL
| K48-linked ubiquitin chain formation with a cullin-RING E3 ligase and Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2-donor UB-acceptor UB-SIL1 peptide | 分子名称: | 5-azanylpentan-2-one, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | 著者 | Liwocha, J, Prabu, J.R, Kleiger, G, Schulman, B.A. | 登録日 | 2023-07-11 | 公開日 | 2024-02-14 | 最終更新日 | 2024-04-17 | 実験手法 | ELECTRON MICROSCOPY (3.76 Å) | 主引用文献 | Mechanism of millisecond Lys48-linked poly-ubiquitin chain formation by cullin-RING ligases. Nat.Struct.Mol.Biol., 31, 2024
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8PPK
| Bat-Hp-CoV Nsp1 and eIF1 bound to the human 40S small ribosomal subunit | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Schubert, K, Karousis, E.D, Ban, I, Lapointe, C.P, Leibundgut, M, Baeumlin, E, Kummerant, E, Scaiola, A, Schoenhut, T, Ziegelmueller, J, Puglisi, J.D, Muehlemann, O, Ban, N. | 登録日 | 2023-07-07 | 公開日 | 2023-10-18 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Universal features of Nsp1-mediated translational shutdown by coronaviruses. Mol.Cell, 83, 2023
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8PPL
| MERS-CoV Nsp1 bound to the human 43S pre-initiation complex | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Schubert, K, Karousis, E.D, Ban, I, Lapointe, C.P, Leibundgut, M, Baeumlin, E, Kummerant, E, Scaiola, A, Schoenhut, T, Ziegelmueller, J, Puglisi, J.D, Muehlemann, O, Ban, N. | 登録日 | 2023-07-07 | 公開日 | 2023-10-18 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | 主引用文献 | Universal features of Nsp1-mediated translational shutdown by coronaviruses. Mol.Cell, 83, 2023
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8PP6
| human RYBP-PRC1 bound to H2AK118ub1 nucleosome | 分子名称: | DNA (215-MER), Histone H2A, Histone H2B, ... | 著者 | Ciapponi, M, Benda, C, Mueller, J. | 登録日 | 2023-07-06 | 公開日 | 2024-04-03 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | Structural basis of the histone ubiquitination read-write mechanism of RYBP-PRC1. Nat.Struct.Mol.Biol., 31, 2024
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8PMQ
| Catalytic module of yeast GID E3 ligase bound to multiphosphorylated Ubc8~ubiquitin | 分子名称: | E3 ubiquitin-protein ligase RMD5, Protein FYV10, Ubiquitin, ... | 著者 | Chrustowicz, J, Sherpa, D, Prabu, R.J, Schulman, B.A. | 登録日 | 2023-06-29 | 公開日 | 2024-01-03 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | 主引用文献 | Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies. Mol.Cell, 84, 2024
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8PJN
| Catalytic module of human CTLH E3 ligase bound to multiphosphorylated UBE2H~ubiquitin | 分子名称: | E3 ubiquitin-protein transferase MAEA, E3 ubiquitin-protein transferase RMND5A, Ubiquitin, ... | 著者 | Chrustowicz, J, Sherpa, D, Prabu, R.J, Schulman, B.A. | 登録日 | 2023-06-23 | 公開日 | 2024-01-03 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies. Mol.Cell, 84, 2024
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8PJ2
| Structure of human 48S translation initiation complex in AUG recognition state after eIF5-induced GTP hydrolysis by eIF2 (48S-2) | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N. | 登録日 | 2023-06-22 | 公開日 | 2024-08-14 | 最終更新日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis for translational control by the human 48S initiation complex. Nat.Struct.Mol.Biol., 2024
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8PJ6
| Structure of human 48S translation initiation complex with initiator tRNA, eIF1A and eIF3 (off-pathway) | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N. | 登録日 | 2023-06-22 | 公開日 | 2024-08-14 | 最終更新日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis for translational control by the human 48S initiation complex. Nat.Struct.Mol.Biol., 2024
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8PJ4
| Structure of human 48S translation initiation complex after eIF5 release (48S-4) | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N. | 登録日 | 2023-06-22 | 公開日 | 2024-08-14 | 最終更新日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for translational control by the human 48S initiation complex. Nat.Struct.Mol.Biol., 2024
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8PJ1
| Structure of human 48S translation initiation complex in open codon scanning state (48S-1) | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N. | 登録日 | 2023-06-22 | 公開日 | 2024-08-14 | 最終更新日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis for translational control by the human 48S initiation complex. Nat.Struct.Mol.Biol., 2024
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8PJ5
| Structure of human 48S translation initiation complex after eIF2 release prior 60S subunit joining (48S-5) | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N. | 登録日 | 2023-06-22 | 公開日 | 2024-08-14 | 最終更新日 | 2024-10-02 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis for translational control by the human 48S initiation complex. Nat.Struct.Mol.Biol., 2024
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