8PJ2
Structure of human 48S translation initiation complex in AUG recognition state after eIF5-induced GTP hydrolysis by eIF2 (48S-2)
This is a non-PDB format compatible entry.
Summary for 8PJ2
Entry DOI | 10.2210/pdb8pj2/pdb |
EMDB information | 17697 |
Descriptor | Eukaryotic translation initiation factor 3 subunit B, 18S rRNA, 40S ribosomal protein S11, ... (55 entities in total) |
Functional Keywords | ribosome, translation, initiation, 48s, eif, human, eukaryotic, factor, codon, scanning, closed |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 53 |
Total formula weight | 2253398.34 |
Authors | Petrychenko, V.,Yi, S.-H.,Liedtke, D.,Peng, B.Z.,Rodnina, M.V.,Fischer, N. (deposition date: 2023-06-22, release date: 2024-08-14) |
Primary citation | Petrychenko, V.,Yi, S.-H.,Liedtke, D.,Peng, B.Z.,Rodnina, M.V.,Fischer, N. Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining Nat.Struct.Mol.Biol., 2024 Cited by DOI: 10.1038/s41594-024-01378-4PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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