8PMQ

Catalytic module of yeast GID E3 ligase bound to multiphosphorylated Ubc8~ubiquitin

Summary for 8PMQ

Entry DOI	10.2210/pdb8pmq/pdb
Related	8PJN
EMDB information	17705 17706 17707 17709 17710 17713 17717 17764
Descriptor	E3 ubiquitin-protein ligase RMD5, Protein FYV10, Ubiquitin-conjugating enzyme E2-24 kDa, ... (5 entities in total)
Functional Keywords	e3 ubiquitin ligase, e2 ubiquitin-conjugating enzyme, phosphorylation, gid, ligase
Biological source	Saccharomyces cerevisiae (baker's yeast) More
Total number of polymer chains	4
Total formula weight	142848.12
Authors	Chrustowicz, J.,Sherpa, D.,Prabu, R.J.,Schulman, B.A. (deposition date: 2023-06-29, release date: 2024-01-03, Last modification date: 2024-02-21)
Primary citation	Chrustowicz, J.,Sherpa, D.,Li, J.,Langlois, C.R.,Papadopoulou, E.C.,Vu, D.T.,Hehl, L.A.,Karayel, O.,Beier, V.,von Gronau, S.,Muller, J.,Prabu, J.R.,Mann, M.,Kleiger, G.,Alpi, A.F.,Schulman, B.A. Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies. Mol.Cell, 84:293-, 2024 Cited by PubMed: 38113892 DOI: 10.1016/j.molcel.2023.11.027 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.53 Å)

Structure validation