8PMQ
Catalytic module of yeast GID E3 ligase bound to multiphosphorylated Ubc8~ubiquitin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (2) | E3 ubiquitin-protein ligase RMD5 | polymer | 421 | 49244.6 | 1 | UniProt (Q12508) Pfam (PF10607) | Saccharomyces cerevisiae (baker's yeast) | Glucose-induced degradation protein 2,Required for meiotic nuclear division protein 5,Sporulation protein RMD5 |
| 2 | B (9) | Protein FYV10 | polymer | 516 | 59975.1 | 1 | UniProt (P40492) Pfam (PF10607) | Saccharomyces cerevisiae (baker's yeast) | Function required for yeast viability protein 10,Glucose-induced degradation protein 9,Probable E3 ubiquitin-protein ligase GID9 |
| 3 | C (E) | Ubiquitin-conjugating enzyme E2-24 kDa | polymer | 218 | 24920.8 | 1 | UniProt (P28263) Pfam (PF00179) | Saccharomyces cerevisiae (baker's yeast) | E2 ubiquitin-conjugating enzyme 8,Glucose-induced degradation protein 3,Ubiquitin carrier protein,Ubiquitin-protein ligase |
| 4 | D (U) | Ubiquitin | polymer | 76 | 8576.8 | 1 | UniProt (P0CG48) Pfam (PF00240) | Homo sapiens (human) | Polyubiquitin-C |
| 5 | E, F (2, 9) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
E: 1 - 218 (UniProt: P28263)
| PDB | External Database | Details |
|---|---|---|
| Lys 85 | Cys 85 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 142717.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 142848.1 |
