7NUJ
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![BU of 7nuj by Molmil](/molmil-images/mine/7nuj) | Crystal structure of holo-SwHPA-Mg (hydroxy ketone aldolase) from Sphingomonas wittichii RW1 | 分子名称: | HpcH/HpaI aldolase, MAGNESIUM ION | 著者 | Laustsen, J, Justo, I, Marsden, S.R, Hanefeld, U, Bento, I. | 登録日 | 2021-03-12 | 公開日 | 2022-09-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Substrate Induced Movement of the Metal Cofactor between Active and Resting State. Angew.Chem.Int.Ed.Engl., 61, 2022
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7T8G
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6UZG
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7OJ1
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6AUY
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![BU of 6auy by Molmil](/molmil-images/mine/6auy) | Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 4-Methyl-6-(3-(3-(methylamino)propyl)phenethyl)pyridin-2-amine | 分子名称: | 4-methyl-6-(2-{3-[3-(methylamino)propyl]phenyl}ethyl)pyridin-2-amine, 5,6,7,8-TETRAHYDROBIOPTERIN, GLYCEROL, ... | 著者 | Li, H, Poulos, T.L. | 登録日 | 2017-09-01 | 公開日 | 2018-07-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Improvement of Cell Permeability of Human Neuronal Nitric Oxide Synthase Inhibitors Using Potent and Selective 2-Aminopyridine-Based Scaffolds with a Fluorobenzene Linker. J. Med. Chem., 60, 2017
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8PP0
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![BU of 8pp0 by Molmil](/molmil-images/mine/8pp0) | Crystal structure of Retinoic Acid Receptor alpha (RXRA) in complexed with JP147 | 分子名称: | 3-[4-[2,3-dihydro-1H-inden-4-yl(methyl)amino]-6-(trifluoromethyl)pyrimidin-2-yl]oxypropanoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha | 著者 | Chaikuad, A, Pollinger, J, Merk, D, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2023-07-05 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure-Guided Design of a Highly Potent Partial RXR Agonist with Superior Physicochemical Properties. J.Med.Chem., 67, 2024
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7OJ2
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![BU of 7oj2 by Molmil](/molmil-images/mine/7oj2) | Bacillus subtilis IMPDH in complex with Ap4A | 分子名称: | GLYCEROL, Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase, PHOSPHATE ION | 著者 | Giammarinaro, P.I, Bange, G. | 登録日 | 2021-05-13 | 公開日 | 2022-09-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Diadenosine tetraphosphate regulates biosynthesis of GTP in Bacillus subtilis. Nat Microbiol, 7, 2022
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5C7W
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![BU of 5c7w by Molmil](/molmil-images/mine/5c7w) | 5'-monophosphate Z:P Guanine Riboswitch bound to hypoxanthine. | 分子名称: | 5'-monophosphate Z:P guanine riboswitch, COBALT HEXAMMINE(III), HYPOXANTHINE | 著者 | Hernandez, A.R, Shao, Y, Hoshika, S, Yang, Z, Shelke, S.A, Herrou, J, Kim, H.-J, Kim, M.-J, Piccirilli, J.A, Benner, S.A. | 登録日 | 2015-06-25 | 公開日 | 2015-08-12 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | 主引用文献 | A Crystal Structure of a Functional RNA Molecule Containing an Artificial Nucleobase Pair. Angew.Chem.Int.Ed.Engl., 54, 2015
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6ARU
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![BU of 6aru by Molmil](/molmil-images/mine/6aru) | Structure of Cetuximab Fab mutant in complex with EGFR extracellular domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab mutant heavy chain Fab fragment,Immunoglobulin gamma-1 heavy chain, ... | 著者 | Christie, M, Christ, D. | 登録日 | 2017-08-23 | 公開日 | 2018-08-29 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure of Cetuximab Fab mutant in complex with EGFR extracellular domain To Be Published
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7NXX
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![BU of 7nxx by Molmil](/molmil-images/mine/7nxx) | Structure of Superoxide Dismutase 1 (SOD1) in complex with nanobody 2 (Nb2). | 分子名称: | COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION, ... | 著者 | Gallardo, R, Rousseau, F, Schymkowitz, J, Ulens, C. | 登録日 | 2021-03-19 | 公開日 | 2022-09-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.189 Å) | 主引用文献 | Identification and rational improvement of a nanobody that suppresses aggregation of mutant SOD1 To Be Published
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7NU0
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![BU of 7nu0 by Molmil](/molmil-images/mine/7nu0) | Crystal Structure of Neisseria gonorrhoeae LeuRS L550A mutant in Complex with ATP and L-leucinol | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-4-METHYL-PENTAN-1-OL, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Pang, L, Strelkov, S.V, Weeks, S.D. | 登録日 | 2021-03-11 | 公開日 | 2022-09-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Partitioning of the initial catalytic steps of leucyl-tRNA synthetase is driven by an active site peptide-plane flip. Commun Biol, 5, 2022
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7T8H
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5C86
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![BU of 5c86 by Molmil](/molmil-images/mine/5c86) | Novel fungal alcohol oxidase with catalytic diversity among the AA5 family, apo form | 分子名称: | Kelch domain-containing protein | 著者 | Urresti, S, Yin, D.T, LaFond, M, Derikvand, F, Berrin, G.J, Henrissat, B, Walton, P.H, Brumer, H, Davies, G.J. | 登録日 | 2015-06-25 | 公開日 | 2015-07-08 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Structure-function characterization reveals new catalytic diversity in the galactose oxidase and glyoxal oxidase family. Nat Commun, 6, 2015
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7WF6
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![BU of 7wf6 by Molmil](/molmil-images/mine/7wf6) | Crystal structure of SNX13 RGS domain | 分子名称: | CHLORIDE ION, Sorting nexin-13 | 著者 | Xu, J, Zhu, J, Liu, J. | 登録日 | 2021-12-26 | 公開日 | 2022-10-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Structural Studies Reveal Unique Non-canonical Regulators of G Protein Signaling Homology (RH) Domains in Sorting Nexins. J.Mol.Biol., 434, 2022
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7NZZ
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8Q8K
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8DGO
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6P8P
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![BU of 6p8p by Molmil](/molmil-images/mine/6p8p) | Structure of P. aeruginosa ATCC27853 HORMA1 | 分子名称: | CALCIUM ION, Uncharacterized protein | 著者 | Ye, Q, Corbett, K.D. | 登録日 | 2019-06-07 | 公開日 | 2019-12-25 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.635 Å) | 主引用文献 | HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity. Mol.Cell, 77, 2020
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5C9E
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![BU of 5c9e by Molmil](/molmil-images/mine/5c9e) | SepL | 分子名称: | BROMIDE ION, SepL | 著者 | Burkinshaw, B.J, Strynadka, N.C.J. | 登録日 | 2015-06-26 | 公開日 | 2015-10-14 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | 主引用文献 | Structural analysis of SepL, an enteropathogenic Escherichia coli type III secretion system gatekeeper protein Acta Crystallogr.,Sect.F, 71, 2015
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6V0M
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6P8V
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6ATZ
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![BU of 6atz by Molmil](/molmil-images/mine/6atz) | HLA-DRB1*1402 in complex with citrullinated fibrinogen peptide | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Fibrinogen beta chain, ... | 著者 | Ting, Y.T, Scally, S.W, Rossjohn, J. | 登録日 | 2017-08-29 | 公開日 | 2017-09-20 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis. Ann. Rheum. Dis., 76, 2017
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7T89
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![BU of 7t89 by Molmil](/molmil-images/mine/7t89) | Light harvesting complex Phycocyanin PC577 from the cryptophyte Hemiselmis pacifica CCMP 706 | 分子名称: | DiCys-(15,16)-Dihydrobiliverdin, PHYCOCYANOBILIN, Phycoerythrin alpha subunit 1, ... | 著者 | Michie, K.A, Curmi, P.C, Harrop, S, Rathbone, H.W. | 登録日 | 2021-12-16 | 公開日 | 2023-02-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Molecular structures reveal the origin of spectral variation in cryptophyte light harvesting antenna proteins. Protein Sci., 32, 2023
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7T8S
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![BU of 7t8s by Molmil](/molmil-images/mine/7t8s) | Light Harvesting complex phycoerythrin PE 566, from the cryptophyte Cryptomonas pyrenoidifera | 分子名称: | Bilin 584 (doubly linked), Bilin 584 (single linked), Bilin 618 (single linked), ... | 著者 | Michie, K.A, Harrop, S.J, Rathbone, H.W, Wilk, K.E, Curmi, P.M.G. | 登録日 | 2021-12-17 | 公開日 | 2023-02-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular structures reveal the origin of spectral variation in cryptophyte light harvesting antenna proteins. Protein Sci., 32, 2023
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8DGM
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![BU of 8dgm by Molmil](/molmil-images/mine/8dgm) | 14-3-3 epsilon bound to phosphorylated PEAK1 (pT1165) peptide | 分子名称: | 1,2-ETHANEDIOL, 14-3-3 protein epsilon, Inactive tyrosine-protein kinase PEAK1 | 著者 | Roy, M.J, Hardy, J.M, Lucet, I.S. | 登録日 | 2022-06-24 | 公開日 | 2023-06-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling. Nat Commun, 14, 2023
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