8DGM

14-3-3 epsilon bound to phosphorylated PEAK1 (pT1165) peptide

Summary for 8DGM

• Entry DOI: 10.2210/pdb8dgm/pdb
• Descriptor: 14-3-3 protein epsilon, Inactive tyrosine-protein kinase PEAK1, 1,2-ETHANEDIOL (3 entities in total)
• Functional Keywords: signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 31907.96

Authors

Roy, M.J.,Hardy, J.M.,Lucet, I.S. (deposition date: 2022-06-24, release date: 2023-06-07, Last modification date: 2023-10-25)

• Primary citation: Roy, M.J.,Surudoi, M.G.,Kropp, A.,Hou, J.,Dai, W.,Hardy, J.M.,Liang, L.Y.,Cotton, T.R.,Lechtenberg, B.C.,Dite, T.A.,Ma, X.,Daly, R.J.,Patel, O.,Lucet, I.S.; Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling.; Nat Commun, 14:3542-3542, 2023; PubMed: 37336884; DOI: 10.1038/s41467-023-38869-9

Experimental method

X-RAY DIFFRACTION (3.2 Å)