PDB: 8861 件ウェブページステータス検索Chemie searchBIRD

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8CBM	Structure of human mitochondrial CCA-adding enzyme in complex with mitochondrial pre-tRNA-Ile 分子名称: 3-hydroxyacyl-CoA dehydrogenase type-2, CCA tRNA nucleotidyltransferase 1, mitochondrial, ... 著者 MEYNIER, V, HARDWICK, S, CATALA, M, ROSKE, J, OERUM, S, CHIRGADZE, D, BARRAUD, P, LUISI, B, TISNE, C. 登録日 2023-01-25 公開日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.14 Å) 主引用文献 Structural basis for human mitochondrial tRNA maturation. Nat Commun, 15, 2024
5F0S	Crystal structure of C-terminal domain of the human DNA primase large subunit with bound DNA template/RNA primer and manganese ion 分子名称: DNA (5'-D(*GP*CP*CP*GP*CP*CP*AP*AP*CP*AP*TP*A)-3'), DNA primase large subunit, IRON/SULFUR CLUSTER, ... 著者 Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D. 登録日 2015-11-28 公開日 2016-03-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome. J.Biol.Chem., 291, 2016
7MLI	Crystal structure of Thermus thermophilus reiterative transcription complex with 5nt oligo-C RNA 分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*CP*TP*AP*CP*GP*GP*AP*TP*G)-3'), DNA (5'-D(P*CP*AP*TP*CP*CP*GP*TP*AP*GP*GP*GP*CP*GP*GP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Liu, Y, Ebright, R.H. 登録日 2021-04-28 公開日 2022-02-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural and mechanistic basis of reiterative transcription initiation. Proc.Natl.Acad.Sci.USA, 119, 2022
6ZOK	SARS-CoV-2-Nsp1-40S complex, focused on body 分子名称: 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S13, ... 著者 Schubert, K, Karousis, E.D, Jomaa, A, Scaiola, A, Echeverria, B, Gurzeler, L.-A, Leibundgut, M, Thiel, V, Muehlemann, O, Ban, N. 登録日 2020-07-07 公開日 2020-07-29 最終更新日 2021-02-10 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation. Nat.Struct.Mol.Biol., 27, 2020
3P87	Structure of human PCNA bound to RNASEH2B PIP box peptide 分子名称: Proliferating cell nuclear antigen, Ribonuclease H2 subunit B 著者 Bubeck, D, Reijns, M.A, Graham, S.C, Astell, K.R, Jones, E.Y, Jackson, A.P. 登録日 2010-10-13 公開日 2011-02-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 PCNA directs type 2 RNase H activity on DNA replication and repair substrates. Nucleic Acids Res., 39, 2011
6AR1	Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications (RT/Duplex (Nat)) 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA, GsI-IIC RT, ... 著者 Stamos, J.L, Lentzsch, A.M, Lambowitz, A.M. 登録日 2017-08-21 公開日 2017-11-29 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications. Mol. Cell, 68, 2017
6AR3	Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications (RT/Duplex (Se-Met)) 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA, GsI-IIC RT, ... 著者 Stamos, J.L, Lentzsch, A.M, Lambowitz, A.M. 登録日 2017-08-21 公開日 2017-11-29 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.41 Å) 主引用文献 Structure of a Thermostable Group II Intron Reverse Transcriptase with Template-Primer and Its Functional and Evolutionary Implications. Mol. Cell, 68, 2017
6ZOL	SARS-CoV-2-Nsp1-40S complex, focused on head 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S12, ... 著者 Schubert, K, Karousis, E.D, Jomaa, A, Scaiola, A, Echeverria, B, Gurzeler, L.-A, Leibundgut, M.L, Thiel, V, Muehlemann, O, Ban, N. 登録日 2020-07-07 公開日 2020-07-22 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation. Nat.Struct.Mol.Biol., 27, 2020
6W1S	Atomic model of the mammalian Mediator complex 分子名称: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ... 著者 Zhao, H, Young, N, Asturias, F. 登録日 2020-03-04 公開日 2021-03-10 実験手法 ELECTRON MICROSCOPY (4.02 Å) 主引用文献 A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers. Cell, 178, 2019
4XJN	Structure of the parainfluenza virus 5 nucleocapsid-RNA complex: an insight into paramyxovirus polymerase activity 分子名称: LEAD (II) ION, Nucleocapsid, RNA (78-MER) 著者 Alayyoubi, M, Leser, G.P, Kors, C.A, Lamb, R.A. 登録日 2015-01-08 公開日 2015-03-18 最終更新日 2017-08-23 実験手法 X-RAY DIFFRACTION (3.11 Å) 主引用文献 Structure of the paramyxovirus parainfluenza virus 5 nucleoprotein-RNA complex. Proc.Natl.Acad.Sci.USA, 112, 2015
8D6J	Human Ago2 bound to miR122(21nt) with PIWI loop swapped to AtAgo10 sequence 分子名称: MAGNESIUM ION, Protein argonaute-2, RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*UP*U)-3') 著者 Xiao, Y, MacRae, I. 登録日 2022-06-06 公開日 2023-05-03 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A tiny loop in the Argonaute PIWI domain tunes small RNA seed strength. Embo Rep., 24, 2023
5NZZ	Crystal structure of phosphorylated p38aMAPK in complex with TAB1 分子名称: MAGNESIUM ION, Mitogen-activated protein kinase 14, NICKEL (II) ION, ... 著者 Nichols, C.E, De Nicola, G.F. 登録日 2017-05-15 公開日 2018-05-30 最終更新日 2018-09-19 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The TAB1-p38 alpha complex aggravates myocardial injury and can be targeted by small molecules. JCI Insight, 3, 2018
4G7O	Crystal structure of Thermus thermophilus transcription initiation complex containing 2 nt of RNA 分子名称: 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', 5'-R(*GP*A)-3', ... 著者 Zhang, Y, Ebright, R.H. 登録日 2012-07-20 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.993 Å) 主引用文献 Structural basis of transcription initiation. Science, 338, 2012
4DRW	Crystal Structure of the Ternary Complex between S100A10, an Annexin A2 N-terminal Peptide and an AHNAK Peptide 分子名称: Neuroblast differentiation-associated protein AHNAK, Protein S100-A10/Annexin A2 chimeric protein 著者 Rezvanpour, A, Lee, T.-W, Junop, M.S, Shaw, G.S. 登録日 2012-02-17 公開日 2012-10-24 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structure of an asymmetric ternary protein complex provides insight for membrane interaction. Structure, 20, 2012
6PZQ	Structure of the human respiratory syncytial virus M2-1 protein in complex with a short positive-sense gene-end RNA 分子名称: Matrix M2-1, RNA (5'-R(P*GP*UP*UP*AP*AP*U)-3'), ZINC ION 著者 Gao, Y, Cao, D, Liang, B. 登録日 2019-08-01 公開日 2020-08-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.703 Å) 主引用文献 Structure of the Human Respiratory Syncytial Virus M2-1 Protein in Complex with a Short Positive-Sense Gene-End RNA. Structure, 28, 2020
6HQA	Molecular structure of promoter-bound yeast TFIID 分子名称: Histone-fold, Subunit (17 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation, ... 著者 Kolesnikova, O, Ben-Shem, A, Luo, J, Ranish, J, Schultz, P, Papai, G. 登録日 2018-09-24 公開日 2018-11-21 最終更新日 2022-03-30 実験手法 ELECTRON MICROSCOPY (7.1 Å) 主引用文献 Molecular structure of promoter-bound yeast TFIID. Nat Commun, 9, 2018
5UH8	Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 4nt RNA 分子名称: DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2017-01-11 公開日 2017-04-12 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (4.176 Å) 主引用文献 Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
5KI6	Human Argonaute-2 bound to a guide RNA with a nucleobase modification at position 1 分子名称: PHENOL, Protein argonaute-2, miR-122 著者 Schirle, N.T, MacRae, I.J. 登録日 2016-06-16 公開日 2016-07-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.153 Å) 主引用文献 Structure-Guided Control of siRNA Off-Target Effects. J.Am.Chem.Soc., 138, 2016
8KG6	Yeast replisome in state I 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ... 著者 Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. 登録日 2023-08-17 公開日 2023-12-06 実験手法 ELECTRON MICROSCOPY (3.07 Å) 主引用文献 Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
7B0H	TgoT_6G12 Ternary complex 分子名称: DNA (5'-D(P*AP*AP*CP*GP*GP*CP*AP*AP*AP*TP*GP*CP*G)-3'), DNA (5'-D(P*CP*GP*CP*AP*TP*T)-3'), DNA polymerase, ... 著者 Samson, C, Legrand, P, Tekpinar, M, Rozenski, J, Abramov, M, Holliger, P, Pinheiro, V, Herdewijn, P, Delarue, M. 登録日 2020-11-19 公開日 2021-01-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution. Biomolecules, 10, 2020
8KG9	Yeast replisome in state III 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (61-mer), ... 著者 Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. 登録日 2023-08-17 公開日 2023-12-06 実験手法 ELECTRON MICROSCOPY (4.52 Å) 主引用文献 Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
8E86	Human DNA polymerase eta-DNA-rC-ended primer-dGMPNPP ternary mismatch complex with Mn2+ 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*AP*TP*TP*GP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, ... 著者 Chang, C, Gao, Y. 登録日 2022-08-25 公開日 2023-02-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299, 2023
8E8D	Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 60s 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, ... 著者 Chang, C, Gao, Y. 登録日 2022-08-25 公開日 2023-02-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299, 2023
8E8G	Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 180s 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Chang, C, Gao, Y. 登録日 2022-08-25 公開日 2023-02-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299, 2023
8E8C	Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 30s 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta, ... 著者 Chang, C, Gao, Y. 登録日 2022-08-25 公開日 2023-02-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299, 2023

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