8D6J
Human Ago2 bound to miR122(21nt) with PIWI loop swapped to AtAgo10 sequence
Summary for 8D6J
Entry DOI | 10.2210/pdb8d6j/pdb |
Descriptor | Protein argonaute-2, RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*UP*U)-3'), MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | argonaute, rnai, microrna, mirna, rna binding protein-rna complex, rna binding protein/rna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 104291.43 |
Authors | Xiao, Y.,MacRae, I. (deposition date: 2022-06-06, release date: 2023-05-03, Last modification date: 2023-10-25) |
Primary citation | Xiao, Y.,Liu, T.M.,MacRae, I.J. A tiny loop in the Argonaute PIWI domain tunes small RNA seed strength. Embo Rep., 24:e55806-e55806, 2023 Cited by PubMed: 37082939DOI: 10.15252/embr.202255806 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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