6W1S

Atomic model of the mammalian Mediator complex

Summary for 6W1S

Entry DOI	10.2210/pdb6w1s/pdb
EMDB information	21514
Descriptor	Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 15, Mediator of RNA polymerase II transcription subunit 16, ... (25 entities in total)
Functional Keywords	mouse mediator, complex, gene regulation
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	25
Total formula weight	975066.81
Authors	Zhao, H.,Young, N.,Asturias, F. (deposition date: 2020-03-04, release date: 2021-03-10)
Primary citation	El Khattabi, L.,Zhao, H.,Kalchschmidt, J.,Young, N.,Jung, S.,Van Blerkom, P.,Kieffer-Kwon, P.,Kieffer-Kwon, K.R.,Park, S.,Wang, X.,Krebs, J.,Tripathi, S.,Sakabe, N.,Sobreira, D.R.,Huang, S.C.,Rao, S.S.P.,Pruett, N.,Chauss, D.,Sadler, E.,Lopez, A.,Nobrega, M.A.,Aiden, E.L.,Asturias, F.J.,Casellas, R. A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers. Cell, 178:1145-1158.e20, 2019 Cited by PubMed: 31402173 DOI: 10.1016/j.cell.2019.07.011 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.02 Å)

Structure validation