3P87

Structure of human PCNA bound to RNASEH2B PIP box peptide

Summary for 3P87

Entry DOI	10.2210/pdb3p87/pdb
Related	1AXC 3P83
Descriptor	Proliferating cell nuclear antigen, Ribonuclease H2 subunit B (2 entities in total)
Functional Keywords	dna binding, dna replication, dna repair, sliding clamp, pcna peptide interacting peptide (pip) motif, pip-box motif, dna clamp, processivity factor, rnase h2, fen-1, ligase, polymerases, helicases, nucleases, nucleus, hydrolase-dna binding protein complex, hydrolase/dna binding protein
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: P12004 Nucleus (Probable): Q5TBB1
Total number of polymer chains	12
Total formula weight	188153.04
Authors	Bubeck, D.,Reijns, M.A.,Graham, S.C.,Astell, K.R.,Jones, E.Y.,Jackson, A.P. (deposition date: 2010-10-13, release date: 2011-02-02, Last modification date: 2023-09-06)
Primary citation	Bubeck, D.,Reijns, M.A.,Graham, S.C.,Astell, K.R.,Jones, E.Y.,Jackson, A.P. PCNA directs type 2 RNase H activity on DNA replication and repair substrates. Nucleic Acids Res., 39:3652-3666, 2011 Cited by PubMed: 21245041 DOI: 10.1093/nar/gkq980 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.99 Å)

Structure validation