5F0S

Crystal structure of C-terminal domain of the human DNA primase large subunit with bound DNA template/RNA primer and manganese ion

Summary for 5F0S

• Entry DOI: 10.2210/pdb5f0s/pdb
• Related: 5F0Q
• Descriptor: DNA primase large subunit, RNA (5'-R(P*GP*GP*CP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*GP*CP*CP*AP*AP*CP*AP*TP*A)-3'), ... (5 entities in total)
• Functional Keywords: tranferase-dna-rna complex, dna primase, large subunit, iron-sulfur cluster, rna, dna, primer, template, triphosphate, initiation site, manganese, replication-dna-rna complex, replication/dna/rna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 56312.84

Authors

Tahirov, T.H.,Baranovskiy, A.G.,Babayeva, N.D. (deposition date: 2015-11-28, release date: 2016-03-23, Last modification date: 2023-09-27)

• Primary citation: Baranovskiy, A.G.,Babayeva, N.D.,Zhang, Y.,Gu, J.,Suwa, Y.,Pavlov, Y.I.,Tahirov, T.H.; Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome.; J.Biol.Chem., 291:10006-10020, 2016; PubMed: 26975377; DOI: 10.1074/jbc.M116.717405

Experimental method

X-RAY DIFFRACTION (3 Å)