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2M8D
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Structure of SRSF1 RRM2 in complex with the RNA 5'-UGAAGGAC-3'
分子名称: RNA (5'-R(*UP*GP*AP*AP*GP*GP*AP*C)-3'), Serine/arginine-rich splicing factor 1
著者Clery, A, Sinha, R, Anczukow, O, Corrionero, A, Moursy, A, Daubner, G, Valcarcel, J, Krainer, A.R, Allain, F.H.T.
登録日2013-05-17
公開日2013-07-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Isolated pseudo-RNA-recognition motifs of SR proteins can regulate splicing using a noncanonical mode of RNA recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
2MXW
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Solution NMR Structure of the OCRE Domain of RBM10
分子名称: RNA-binding protein 10
著者Martin, B.T, Geralt, M, Serrano, P, Wuthrich, K, Joint Center for Structural Genomics (JCSG)
登録日2015-01-20
公開日2015-04-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of the OCRE Domain of RBM10
To be Published
3J6Y
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S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 2 degree rotation (Class I)
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ...
著者Koh, C.S, Brilot, A.F, Grigorieff, N, Korostelev, A.A.
登録日2014-04-16
公開日2014-06-11
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center.
Proc.Natl.Acad.Sci.USA, 111, 2014
2MXV
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NMR structure of the first Zinc Finger domain of RBM10
分子名称: RNA-binding protein 10, ZINC ION
著者Serrano, P, Wuthrich, K, Geralt, M, Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
登録日2015-01-16
公開日2015-01-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR structure of the first Zinc Finger domain of RBM10
To be Published
3K0J
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Crystal structure of the E. coli ThiM riboswitch in complex with thiamine pyrophosphate and the U1A crystallization module
分子名称: MAGNESIUM ION, RNA (87-MER), THIAMINE DIPHOSPHATE, ...
著者Kulshina, N, Edwards, T.E, Ferre-D'Amare, A.R.
登録日2009-09-24
公開日2009-12-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Thermodynamic analysis of ligand binding and ligand binding-induced tertiary structure formation by the thiamine pyrophosphate riboswitch.
Rna, 16, 2010
6HHQ
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Crystal structure of compound C45 bound to the yeast 80S ribosome
分子名称: (3~{R})-3-[(1~{S})-2-[(1~{S},4~{a}~{R},6~{S},7~{S},8~{a}~{R})-6,7-bis(chloranyl)-5,5,8~{a}-trimethyl-2-methylidene-3,4,4~{a},6,7,8-hexahydro-1~{H}-naphthalen-1-yl]-1-oxidanyl-ethyl]pyrrolidine-2,5-dione, 18S ribosomal RNA, 25S ribosomal RNA, ...
著者Pellegrino, S, Vanderwal, C.D, Yusupov, M.
登録日2018-08-28
公開日2019-02-20
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3.10000038 Å)
主引用文献Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome.
Nucleic Acids Res., 47, 2019
6HMO
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Solution structure of the RNA duplex formed by the 5'-end of U1snRNA and the 5'-splice site of SMN2 exon7 in complex with the SMN-C5 splicing modifier
分子名称: 2-(8-fluoranyl-2-methyl-imidazo[1,2-a]pyridin-6-yl)-7-(4-methylpiperazin-1-yl)pyrido[1,2-a]pyrimidin-4-one, RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
著者Campagne, S, Allain, F.H.
登録日2018-09-12
公開日2019-08-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis of a small molecule targeting RNA for a specific splicing correction.
Nat.Chem.Biol., 15, 2019
4ITS
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Crystal structure of the catalytic domain of human Pus1 with MES in the active site
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, tRNA pseudouridine synthase A, ...
著者Czudnochowski, N, Finer-Moore, J.S, Stroud, R.M.
登録日2013-01-18
公開日2013-06-05
最終更新日2013-10-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献In Human Pseudouridine Synthase 1 (hPus1), a C-Terminal Helical Insert Blocks tRNA from Binding in the Same Orientation as in the Pus1 Bacterial Homologue TruA, Consistent with Their Different Target Selectivities.
J.Mol.Biol., 425, 2013
4IQM
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Crystal structure of the catalytic domain of human Pus1
分子名称: tRNA pseudouridine synthase A, mitochondrial
著者Czudnochowski, N, Finer-Moore, J.S, Stroud, R.M.
登録日2013-01-11
公開日2013-06-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献In Human Pseudouridine Synthase 1 (hPus1), a C-Terminal Helical Insert Blocks tRNA from Binding in the Same Orientation as in the Pus1 Bacterial Homologue TruA, Consistent with Their Different Target Selectivities.
J.Mol.Biol., 425, 2013
3J6X
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BU of 3j6x by Molmil
S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 5 degree rotation (Class II)
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ...
著者Koh, C.S, Brilot, A.F, Grigorieff, N, Korostelev, A.A.
登録日2014-04-16
公開日2014-06-11
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center.
Proc.Natl.Acad.Sci.USA, 111, 2014
3J77
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Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class II - rotated ribosome with 1 tRNA)
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ...
著者Svidritskiy, E, Brilot, A.F, Koh, C.S, Grigorieff, N, Korostelev, A.A.
登録日2014-05-29
公開日2014-08-06
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献Structures of Yeast 80S Ribosome-tRNA Complexes in the Rotated and Nonrotated Conformations.
Structure, 22, 2014
6I7O
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The structure of a di-ribosome (disome) as a unit for RQC and NGD quality control pathways recognition.
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Tesina, P, Cheng, J, Becker, T, Beckmann, R.
登録日2018-11-16
公開日2019-01-16
最終更新日2019-03-13
実験手法ELECTRON MICROSCOPY (5.3 Å)
主引用文献Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathways.
EMBO J., 38, 2019
6HD7
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Cryo-EM structure of the ribosome-NatA complex
分子名称: 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, 5.8S rRNA, 5S rRNA, ...
著者Knorr, A.G, Becker, T, Beckmann, R.
登録日2018-08-17
公開日2018-12-19
最終更新日2019-01-16
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Ribosome-NatA architecture reveals that rRNA expansion segments coordinate N-terminal acetylation.
Nat. Struct. Mol. Biol., 26, 2019
2K8Q
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BU of 2k8q by Molmil
NMR Structure of Shq1p N-terminal domain
分子名称: Protein SHQ1
著者Godin, K.S, Varani, G.
登録日2008-09-18
公開日2009-05-05
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The box H/ACA snoRNP assembly factor Shq1p is a chaperone protein homologous to Hsp90 cochaperones that binds to the Cbf5p enzyme
J.Mol.Biol., 390, 2009
3KTP
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Structural basis of GW182 recognition by poly(A)-binding protein
分子名称: Polyadenylate-binding protein 1, Trinucleotide repeat-containing gene 6C protein
著者Kozlov, G, Gehring, K.
登録日2009-11-25
公開日2010-02-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding protein.
J.Biol.Chem., 285, 2010
3IWN
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BU of 3iwn by Molmil
Co-crystal structure of a bacterial c-di-GMP riboswitch
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), C-di-GMP riboswitch, U1 small nuclear ribonucleoprotein A
著者Kulshina, N, Baird, N.J, Ferre-D'Amare, A.R.
登録日2009-09-02
公開日2009-11-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Recognition of the bacterial second messenger cyclic diguanylate by its cognate riboswitch.
Nat.Struct.Mol.Biol., 16, 2009
3J78
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BU of 3j78 by Molmil
Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class I - non-rotated ribosome with 2 tRNAs)
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ...
著者Svidritskiy, E, Brilot, A.F, Koh, C.S, Grigorieff, N, Korostelev, A.A.
登録日2014-05-29
公開日2014-08-06
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (6.3 Å)
主引用文献Structures of Yeast 80S Ribosome-tRNA Complexes in the Rotated and Nonrotated Conformations.
Structure, 22, 2014
3JCT
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Cryo-em structure of eukaryotic pre-60S ribosomal subunits
分子名称: 60S ribosomal protein L11-A, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ...
著者Wu, S, Kumcuoglu, B, Yan, K.G, Brown, H, Zhang, Y.X, Tan, D, Gamalinda, M, Yuan, Y, Li, Z.F, Jakovljevic, J, Ma, C.Y, Lei, J.L, Dong, M.Q, Woolford Jr, J.L, Gao, N.
登録日2016-03-09
公開日2016-06-01
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Diverse roles of assembly factors revealed by structures of late nuclear pre-60S ribosomes
Nature, 534, 2016
3KUJ
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Crystal structure of C-terminal domain of PABPC1 in complex with binding region of eRF3a
分子名称: GSPT1 protein, Polyadenylate-binding protein 1, SULFATE ION
著者Kozlov, G, Gehring, K.
登録日2009-11-27
公開日2010-05-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Molecular basis of eRF3 recognition by the MLLE domain of poly(A)-binding protein.
Plos One, 5, 2010
3KUS
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Crystal structure of the MLLE domain of poly(A)-binding protein in complex with the binding region of Paip2
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, PAIP2 protein, ...
著者Kozlov, G, Gehring, K.
登録日2009-11-27
公開日2010-02-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Molecular Determinants of PAM2 Recognition by the MLLE Domain of Poly(A)-Binding Protein.
J.Mol.Biol., 397, 2010
3KUI
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Crystal structure of C-terminal domain of PABPC1 in complex with binding region of eRF3a
分子名称: GSPT1 protein, Polyadenylate-binding protein 1, SULFATE ION, ...
著者Kozlov, G, Gehring, K.
登録日2009-11-27
公開日2010-05-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular basis of eRF3 recognition by the MLLE domain of poly(A)-binding protein.
Plos One, 5, 2010
3KUR
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Crystal structure of the MLLE domain of poly(A)-binding protein
分子名称: CHLORIDE ION, Polyadenylate-binding protein 1
著者Kozlov, G, Gehring, K.
登録日2009-11-27
公開日2010-02-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular Determinants of PAM2 Recognition by the MLLE Domain of Poly(A)-Binding Protein.
J.Mol.Biol., 397, 2010
2PE8
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Crystal structure of the UHM domain of human SPF45 (free form)
分子名称: Splicing factor 45
著者Corsini, L, Basquin, J, Hothorn, M, Sattler, M.
登録日2007-04-02
公開日2007-06-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献U2AF-homology motif interactions are required for alternative splicing regulation by SPF45.
Nat.Struct.Mol.Biol., 14, 2007
3LPY
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BU of 3lpy by Molmil
Crystal structure of the RRM domain of CyP33
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Peptidyl-prolyl cis-trans isomerase E, SULFATE ION
著者Wang, Z, Patel, D.J.
登録日2010-02-07
公開日2010-07-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression.
Cell(Cambridge,Mass.), 141, 2010
3KUT
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Crystal structure of the MLLE domain of poly(A)-binding protein in complex with the binding region of Paip2
分子名称: CHLORIDE ION, PAIP2 protein, Polyadenylate-binding protein 1
著者Kozlov, G, Gehring, K.
登録日2009-11-27
公開日2010-02-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Molecular Determinants of PAM2 Recognition by the MLLE Domain of Poly(A)-Binding Protein.
J.Mol.Biol., 397, 2010

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