3K0J

Crystal structure of the E. coli ThiM riboswitch in complex with thiamine pyrophosphate and the U1A crystallization module

Summary for 3K0J

Entry DOI	10.2210/pdb3k0j/pdb
Descriptor	U1 small nuclear ribonucleoprotein A, RNA (87-MER), THIAMINE DIPHOSPHATE, ... (4 entities in total)
Functional Keywords	riboswitch, rna, thi-box, thim, u1a protein, acetylation, mrna processing, mrna splicing, nucleus, phosphoprotein, ribonucleoprotein, rna-binding, spliceosome, rna-rna binding protein complex, rna/rna binding protein
Biological source	Homo sapiens (human)
Cellular location	Nucleus: P09012
Total number of polymer chains	6
Total formula weight	101404.16
Authors	Kulshina, N.,Edwards, T.E.,Ferre-D'Amare, A.R. (deposition date: 2009-09-24, release date: 2009-12-22, Last modification date: 2024-02-21)
Primary citation	Kulshina, N.,Edwards, T.E.,Ferre-D'Amare, A.R. Thermodynamic analysis of ligand binding and ligand binding-induced tertiary structure formation by the thiamine pyrophosphate riboswitch. Rna, 16:186-196, 2010 Cited by PubMed: 19948769 DOI: 10.1261/rna.1847310 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation