3K0J

Crystal structure of the E. coli ThiM riboswitch in complex with thiamine pyrophosphate and the U1A crystallization module

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003723	molecular_function	RNA binding
B	0003676	molecular_function	nucleic acid binding
B	0003723	molecular_function	RNA binding
C	0003676	molecular_function	nucleic acid binding
C	0003723	molecular_function	RNA binding
D	0003676	molecular_function	nucleic acid binding
D	0003723	molecular_function	RNA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE TPP E 601

Chain	Residue
E	G14
E	G78
E	MG701
E	MG702
E	U15
E	G40
E	G42
E	A43
E	C57
E	G72
E	G76
E	C77

---

site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE TPP F 602

Chain	Residue
F	G114
F	G140
F	G142
F	A143
F	C157
F	C158
F	G172
F	A175
F	G176
F	C177
F	MG703
F	MG708

---

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG E 701

Chain	Residue
E	TPP601

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG E 702

Chain	Residue
E	G60
E	G78
E	TPP601

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG F 703

Chain	Residue
F	U159
F	G160
F	G178
F	TPP602
F	MG708

---

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG E 704

Chain	Residue
E	C74

---

site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG E 705

Chain	Residue
E	G36

---

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG E 706

Chain	Residue
E	A80
E	G81

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG E 707

Chain	Residue
E	U64
E	G65
E	G66

---

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG F 708

Chain	Residue
F	G178
F	TPP602
F	MG703

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	MOD_RES: N-acetylalanine => ECO:0000269|Ref.4, ECO:0007744|PubMed:19413330

Chain	Residue	Details
A	ALA202
B	ALA302
C	ALA402
D	ALA502

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	LYS260
B	LYS360
C	LYS460
D	LYS560

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