Crystal structure of the MLLE domain of poly(A)-binding protein in complex with the binding region of Paip2

Summary for 3KUS

Related3KUR 3KUT
DescriptorPolyadenylate-binding protein 1, PAIP2 protein, GLYCEROL, ... (5 entities in total)
Functional Keywordsprotein-protein complex, methylation, mrna processing, mrna splicing, nucleus, phosphoprotein, rna-binding, spliceosome, protein binding
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm P11940
Total number of polymer chains4
Total molecular weight22405.87
Kozlov, G.,Gehring, K. (deposition date: 2009-11-27, release date: 2010-02-09, Last modification date: 2011-07-13)
Primary citation
Kozlov, G.,Menade, M.,Rosenauer, A.,Nguyen, L.,Gehring, K.
Molecular Determinants of PAM2 Recognition by the MLLE Domain of Poly(A)-Binding Protein.
J.Mol.Biol., 397:397-407, 2010
PubMed: 20096703 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2010.01.032
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.20450 0.7% 2.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-11-25