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3KUS

Crystal structure of the MLLE domain of poly(A)-binding protein in complex with the binding region of Paip2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Polyadenylate-binding protein 1polymer889421.92UniProt (P11940)
Pfam (PF00658)
Homo sapiens (human)Poly(A)-binding protein 1, PABP 1
2C, D
(C, D)
PAIP2 proteinpolymer151615.82UniProt (Q6FID7)
Pfam (PF07145)
UniProt (by SIFTS) (Q9BPZ3)
Homo sapiens
3E
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
4F
(B)
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.31Chemie (EPE)
5G, H, I, J
(A, B, C, D)
waterwater18.0128Chemie (HOH)
Sequence modifications
A, B: 544 - 626 (UniProt: P11940)
PDBExternal DatabaseDetails
Gly 539-expression tag
Pro 540-expression tag
Leu 541-expression tag
Gly 542-expression tag
Ser 543-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight22075.5
Non-Polymers*Number of molecules2
Total formula weight330.4
All*Total formula weight22405.9
*Water molecules are not included.

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PDB entries from 2025-12-17

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