PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

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7ZK3	Structure of 1PBC- and calcium-bound mTMEM16A(ac) chloride channel at 2.85 A resolution 分子名称: 1-Hydroxy-3-(trifluoromethyl)pyrido[1,2-a]benzimidazole-4-carbonitrile, Anoctamin-1, CALCIUM ION 著者 Lam, A.K.M, Rutz, S, Dutzler, R. 登録日 2022-04-12 公開日 2022-05-25 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (2.85 Å) 主引用文献 Inhibition mechanism of the chloride channel TMEM16A by the pore blocker 1PBC. Nat Commun, 13, 2022
7ZKF	Crystal Structure of human Brachyury G177D variant in complex with CF-5-86 分子名称: PHOSPHATE ION, T-box transcription factor T, UNKNOWN LIGAND 著者 Newman, J.A, Gavard, A, Aitkenhead, H, Imprachim, N, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Bountra, C, Gileadi, O. 登録日 2022-04-12 公開日 2022-06-22 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Crystal Structure of human Brachyury G177D variant in complex with CF-5-86 To Be Published
7ZL2	Crystal Structure of human Brachyury G177D variant in complex with Molpolrt-039-246-810 分子名称: T-box transcription factor T, UNKNOWN LIGAND 著者 Newman, J.A, Gavard, A, Aitkenhead, H, Imprachim, N, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Bountra, C, Gileadi, O. 登録日 2022-04-13 公開日 2022-06-22 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structure of human Brachyury G177D variant in complex with Molpolrt-039-246-810 To Be Published
7ZK2	Crystal Structure of human Brachyury G177D variant in complex with CSC027898502 分子名称: N-[4-(2-morpholin-4-yl-1,3-thiazol-4-yl)phenyl]ethanamide, PHOSPHATE ION, T-box transcription factor T 著者 Newman, J.A, Gavard, A, Aitkenhead, H, Imprachim, N, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Bountra, C, Gileadi, O. 登録日 2022-04-12 公開日 2022-06-22 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal Structure of human Brachyury G177D variant in complex with CSC027898502 To Be Published
7ZNO	Crystal Structure of Unlinked NS2B_NS3 Protease from Zika Virus in Complex with Boronate Inhibitor MI-2270 分子名称: Serine protease NS3, Serine protease subunit NS2B, [(1R)-1-[[(2S)-6-azanyl-2-[[(2S)-6-azanyl-2-[2-[3-(4-carbamimidamido-3-oxidanylidene-pentyl)phenyl]ethanoylamino]hexanoyl]amino]hexanoyl]amino]-3-methyl-butyl]boronic acid 著者 Huber, S, Heine, A, Steinmetzer, T. 登録日 2022-04-21 公開日 2022-06-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Boroleucine-Derived Covalent Inhibitors of the ZIKV Protease. Chemmedchem, 18, 2023
7ZVM	Thermococcus barophilus phosphomannose isomerase protein structure at 1.6 A 分子名称: MAGNESIUM ION, Mannose-6-phosphate isomerase 著者 Hoh, F, Calio, A. 登録日 2022-05-16 公開日 2022-08-24 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Unravelling the Adaptation Mechanisms to High Pressure in Proteins. Int J Mol Sci, 23, 2022
7ZHI	Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum with bound inhibitor indole 分子名称: Aspartate carbamoyltransferase, INDOLE, SULFATE ION 著者 Wang, C, Zhang, B. 登録日 2022-04-06 公開日 2022-08-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.946 Å) 主引用文献 Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials. J.Am.Chem.Soc., 144, 2022
7ZGM	Plant N-glycan specific alpha-1,3-mannosidase 分子名称: CALCIUM ION, Glycoside hydrolase family 92 protein, POTASSIUM ION, ... 著者 Basle, A, Crouch, L, Bolam, D. 登録日 2022-04-04 公開日 2022-09-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Plant N -glycan breakdown by human gut Bacteroides. Proc.Natl.Acad.Sci.USA, 119, 2022
7ZGS	Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum with bound inhibitor 2-phenylethan-1-amine 分子名称: 3-PHENYLPROPYLAMINE, Aspartate carbamoyltransferase, SODIUM ION, ... 著者 Wang, C, Zhang, B. 登録日 2022-04-04 公開日 2022-08-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.349 Å) 主引用文献 Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials. J.Am.Chem.Soc., 144, 2022
7ZGN	Plant/insect N-glycan active PNGase 分子名称: Glpgli family protein 著者 Basle, A, Crouch, L, Bolam, D. 登録日 2022-04-04 公開日 2022-09-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Plant N -glycan breakdown by human gut Bacteroides. Proc.Natl.Acad.Sci.USA, 119, 2022
7ZP2	Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum in complex with BDA-04 分子名称: Aspartate carbamoyltransferase, SODIUM ION, SULFATE ION, ... 著者 Wang, C, Zhang, B, Groves, M.R. 登録日 2022-04-26 公開日 2022-08-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.292 Å) 主引用文献 Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials. J.Am.Chem.Soc., 144, 2022
7ZST	Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum in complex with FLA-01 分子名称: 2-azanyl-~{N}-(2-methoxyethyl)-5-phenyl-thiophene-3-carboxamide, Aspartate carbamoyltransferase, GLYCEROL, ... 著者 Wang, C, Zhang, B, Groves, M.R. 登録日 2022-05-08 公開日 2022-08-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials. J.Am.Chem.Soc., 144, 2022
7ZH9	Uba1 in complex with ATP 分子名称: ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... 著者 Misra, M, Schindelin, H. 登録日 2022-04-05 公開日 2022-08-31 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Structures of UBA6 explain its dual specificity for ubiquitin and FAT10. Nat Commun, 13, 2022
7ZUF	Saccharomyces cerevisiae L-BC virus, open particle, C5 reconstruction 分子名称: Major capsid protein 著者 Grybchuk, D, Prochazkova, M, Fuzik, T, Konovalovas, A, Serva, S, Yurchenko, V, Plevka, P. 登録日 2022-05-12 公開日 2022-09-07 実験手法 ELECTRON MICROSCOPY (10 Å) 主引用文献 Structures of L-BC virus and its open particle provide insight into Totivirus capsid assembly. Commun Biol, 5, 2022
8A61	S. cerevisiae apo phosphorylated APC/C 分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ... 著者 Barford, D, Fernandez-Vazquez, E, Zhang, Z, Yang, J. 登録日 2022-06-16 公開日 2022-08-31 実験手法 ELECTRON MICROSCOPY (5.4 Å) 主引用文献 Cryo-EM structure of the S. cerevisiae apo phosphorylated APC/C To Be Published
7ZID	Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum in complex with BDA-14 分子名称: Aspartate carbamoyltransferase, GLYCEROL, SULFATE ION, ... 著者 Wang, C, Zhang, B. 登録日 2022-04-07 公開日 2022-08-31 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials. J.Am.Chem.Soc., 144, 2022
8A3T	S. cerevisiae APC/C-Cdh1 complex 分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 11, Anaphase-promoting complex subunit 2, ... 著者 Barford, D, Vazquez-Fernandez, E, Zhang, Z, Yang, J. 登録日 2022-06-09 公開日 2022-08-31 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Cryo-EM structure of the S. cerevisiae APC/C-Cdh1 complex To Be Published
7ZMD	Ketosynthase domain of module 3 from Brevibacillus Brevis orphan BGC11 分子名称: Putative polyketide synthase 著者 Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T. 登録日 2022-04-19 公開日 2022-09-21 最終更新日 2023-04-05 実験手法 ELECTRON MICROSCOPY (2.93 Å) 主引用文献 The structure of a polyketide synthase bimodule core. Sci Adv, 8, 2022
7ZMA	Ketosynthase domain of module 4 from Brevibacillus Brevis orphan BGC11 分子名称: Putative polyketide synthase 著者 Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T. 登録日 2022-04-19 公開日 2022-09-21 最終更新日 2023-04-05 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 The structure of a polyketide synthase bimodule core. Sci Adv, 8, 2022
7ZOS	Class 1 Phytoglobin from Sugar beet (BvPgb1.2) 分子名称: CYANIDE ION, HEXACYANOFERRATE(3-), Non-symbiotic hemoglobin class 1, ... 著者 Nyblom, M, Christensen, S, Eriksson, N, Bulow, L. 登録日 2022-04-26 公開日 2022-09-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Oxidative Implications of Substituting a Conserved Cysteine Residue in Sugar Beet Phytoglobin BvPgb 1.2. Antioxidants, 11, 2022
8A43	Human RNA polymerase I 分子名称: DNA-directed RNA polymerase I subunit RPA1, DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA2, ... 著者 Daiss, J.L, Pilsl, M, Straub, K, Bleckmann, A, Hoecherl, M, Heiss, F.B, Abascal-Palacios, G, Ramsay, E, Tluckova, K, Mars, J.C, Fuertges, T, Bruckmann, A, Rudack, T, Bernecky, C, Lamour, V, Panov, K, Vannini, A, Moss, T, Engel, C. 登録日 2022-06-10 公開日 2022-08-31 最終更新日 2022-11-02 実験手法 ELECTRON MICROSCOPY (4.09 Å) 主引用文献 The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans. Life Sci Alliance, 5, 2022
8A9U	Full AAV3B-VP1KO virion 分子名称: Capsid protein VP1 著者 Arriaga, I, Abrescia, N.G.A. 登録日 2022-06-29 公開日 2022-09-21 最終更新日 2022-11-23 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Cellular and Structural Characterization of VP1 and VP2 Knockout Mutants of AAV3B Serotype and Implications for AAV Manufacturing. Hum Gene Ther, 33, 2022
7ZTY	Structure of Vps39 N-terminal domain from Chaetomium thermophilum 分子名称: CNH domain-containing protein 著者 Kiontke, S, Ungermann, C, Kuemmel, D. 登録日 2022-05-11 公開日 2022-09-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Structure of the HOPS tethering complex, a lysosomal membrane fusion machinery. Elife, 11, 2022
7ZM0	Structure of UCHL1 in complex with GK13S inhibitor 分子名称: (3S)-1-(iminomethyl)-N-[1-[4-(pent-4-ynylcarbamoyl)phenyl]imidazol-4-yl]pyrrolidine-3-carboxamide, Ubiquitin carboxyl-terminal hydrolase isozyme L1 著者 Grethe, C, Gersch, M. 登録日 2022-04-18 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Structural basis for specific inhibition of the deubiquitinase UCHL1. Nat Commun, 13, 2022
7ZYH	Crystal structure of human CPSF30 in complex with hFip1 分子名称: Cleavage and polyadenylation specificity factor subunit 4, Isoform 4 of Pre-mRNA 3'-end-processing factor FIP1, ZINC ION 著者 Muckenfuss, L.M, Jinek, M, Migenda Herranz, A.C, Clerici, M. 登録日 2022-05-24 公開日 2022-09-14 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Fip1 is a multivalent interaction scaffold for processing factors in human mRNA 3' end biogenesis. Elife, 11, 2022

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