7ZYH

Crystal structure of human CPSF30 in complex with hFip1

Summary for 7ZYH

Entry DOI	10.2210/pdb7zyh/pdb
Descriptor	Cleavage and polyadenylation specificity factor subunit 4, Isoform 4 of Pre-mRNA 3'-end-processing factor FIP1, ZINC ION, ... (4 entities in total)
Functional Keywords	complex, 3' end processing, cpsf, gene regulation
Biological source	Homo sapiens (human) More
Total number of polymer chains	12
Total formula weight	93380.12
Authors	Muckenfuss, L.M.,Jinek, M.,Migenda Herranz, A.C.,Clerici, M. (deposition date: 2022-05-24, release date: 2022-09-14, Last modification date: 2022-09-21)
Primary citation	Muckenfuss, L.M.,Migenda Herranz, A.C.,Boneberg, F.M.,Clerici, M.,Jinek, M. Fip1 is a multivalent interaction scaffold for processing factors in human mRNA 3' end biogenesis. Elife, 11:-, 2022 Cited by PubMed: 36073787 DOI: 10.7554/eLife.80332 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation