7ZYH
Crystal structure of human CPSF30 in complex with hFip1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J (A, D, G, J) | Cleavage and polyadenylation specificity factor subunit 4 | polymer | 64 | 7482.7 | 4 | UniProt (O95639) Pfam (PF00642) | Homo sapiens (human) | Cleavage and polyadenylation specificity factor 30 kDa subunit,CPSF 30 kDa subunit,NS1 effector domain-binding protein 1,Neb-1,No arches homolog |
| 2 | B, C, E, F, H... (B, C, E, F, H...) | Isoform 4 of Pre-mRNA 3'-end-processing factor FIP1 | polymer | 69 | 7865.8 | 8 | UniProt (Q6UN15-4) Pfam (PF05182) UniProt (by SIFTS) (Q6UN15) | Homo sapiens (human) | hFip1,FIP1-like 1 protein,Factor interacting with PAP,Rearranged in hypereosinophilia |
| 3 | M, N, O, P, Q... (A, D, G, J) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 4 | AA, BA, CA, DA, EA... (G, H, I, J, K...) | water | water | 18.0 | 98 | Chemie (HOH) |
Sequence modifications
A, D, G, J: 118 - 178 (UniProt: O95639)
B, C, E, F, H, I, K, L: 130 - 195 (UniProt: Q6UN15-4)
| PDB | External Database | Details |
|---|---|---|
| Ser 115 | - | expression tag |
| Asn 116 | - | expression tag |
| Ala 117 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 127 | - | expression tag |
| Asn 128 | - | expression tag |
| Ala 129 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 92856.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 523.3 | |
| All* | Total formula weight | 93380.1 |
