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PDB: 6 results
7ZK3
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BU of 7zk3 by Molmil
Structure of 1PBC- and calcium-bound mTMEM16A(ac) chloride channel at 2.85 A resolution
Descriptor: 1-Hydroxy-3-(trifluoromethyl)pyrido[1,2-a]benzimidazole-4-carbonitrile, Anoctamin-1, CALCIUM ION
Authors:Lam, A.K.M, Rutz, S, Dutzler, R.
Deposit date:2022-04-12
Release date:2022-05-25
Last modified:2022-06-01
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Inhibition mechanism of the chloride channel TMEM16A by the pore blocker 1PBC.
Nat Commun, 13, 2022
7P60
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BU of 7p60 by Molmil
Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb4 at 1:0.5 ratio
Descriptor: Volume-regulated anion channel subunit LRRC8A, synthetic nanobody Sb4
Authors:Deneka, D, Rutz, S, Sawicka, M.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Allosteric modulation of LRRC8 channels by targeting their cytoplasmic domains.
Nat Commun, 12, 2021
7P5V
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BU of 7p5v by Molmil
Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb1
Descriptor: Synthetic nanobody Sb1, Volume-regulated anion channel subunit LRRC8A
Authors:Deneka, D, Rutz, S, Sawicka, M.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Allosteric modulation of LRRC8 channels by targeting their cytoplasmic domains.
Nat Commun, 12, 2021
7P5Y
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BU of 7p5y by Molmil
Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb3
Descriptor: Volume-regulated anion channel subunit LRRC8A, synthetic nanobody Sb3
Authors:Deneka, D, Rutz, S, Sawicka, M.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Allosteric modulation of LRRC8 channels by targeting their cytoplasmic domains.
Nat Commun, 12, 2021
7P5W
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BU of 7p5w by Molmil
Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb2
Descriptor: Volume-regulated anion channel subunit LRRC8A, synthetic nanobody Sb2
Authors:Deneka, D, Rutz, S, Sawicka, M.
Deposit date:2021-07-15
Release date:2021-09-15
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Allosteric modulation of LRRC8 channels by targeting their cytoplasmic domains.
Nat Commun, 12, 2021
7P6K
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BU of 7p6k by Molmil
Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb5
Descriptor: Volume-regulated anion channel subunit LRRC8A, synthetic nanobody Sb5
Authors:Deneka, D, Rutz, S, Sawicka, M.
Deposit date:2021-07-16
Release date:2021-09-15
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Allosteric modulation of LRRC8 channels by targeting their cytoplasmic domains.
Nat Commun, 12, 2021

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