PDB: 1811 件ウェブページステータス検索Chemie searchBIRD

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1UPV	Crystal structure of the human Liver X receptor beta ligand binding domain in complex with a synthetic agonist 分子名称: N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE, OXYSTEROLS RECEPTOR LXR-BETA 著者 Hoerer, S, Schmid, A, Heckel, A, Budzinski, R.M, Nar, H. 登録日 2003-10-13 公開日 2004-10-20 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of the Human Liver X Receptor Beta Ligand-Binding Domain in Complex with a Synthetic Agonist J.Mol.Biol., 334, 2003
1UPW	Crystal structure of the human Liver X receptor beta ligand binding domain in complex with a synthetic agonist 分子名称: N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE, OXYSTEROLS RECEPTOR LXR-BETA 著者 Hoerer, S, Schmid, A, Heckel, A, Budzinski, R.M, Nar, H. 登録日 2003-10-13 公開日 2004-10-20 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of the Human Liver X Receptor Beta Ligand-Binding Domain in Complex with a Synthetic Agonist J.Mol.Biol., 334, 2003
1R6G	Crystal structure of the thyroid hormone receptor beta ligand binding domain in complex with a beta selective compound 分子名称: 2-[3,5-DIBROMO-4-(4-HYDROXY-3-{HYDROXY[(2-PHENYLETHYL)AMINO]METHYL}PHENOXY)PHENYL]ETHANE-1,1-DIOL, Thyroid hormone receptor beta-1 著者 Hangeland, J.J, Dejneka, T, Friends, T.J, Devasthale, P, Mellstrom, K, Sandberg, J, Grynfarb, M, Doweyko, A.M, Sack, J.S, Einspahr, H, Farnegardh, M, Husman, B, Ljunggren, J, Koehler, K, Sheppard, C, Malm, J, Ryono, D.E. 登録日 2003-10-15 公開日 2005-02-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Thyroid receptor ligands. Part 2: Thyromimetics with improved selectivity for the thyroid hormone receptor beta. Bioorg.Med.Chem.Lett., 14, 2004
1RDT	Crystal Structure of a new rexinoid bound to the RXRalpha ligand binding doamin in the RXRalpha/PPARgamma heterodimer 分子名称: (S)-(2E)-3[4-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-2-NAPHTHALENYL)TETRAHYDRO-1-BENZOFURAN-2-YL]-2-PROPENOIC ACID, 2-(2-BENZOYL-PHENYLAMINO)-3-{4-[2-(5-METHYL-2-PHENYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-PROPIONIC ACID, LxxLL motif coactivator, ... 著者 Haffner, C.D, Lenhard, J.M, Miller, A.B, McDougald, D.L, Dwornik, K, Ittoop, O.R, Gampe Jr, R.T, Xu, H.E, Blanchard, S, Montana, V.G. 登録日 2003-11-06 公開日 2004-11-09 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-based design of potent retinoid X receptor alpha agonists. J.Med.Chem., 47, 2004
1RJK	crystal structure of the rat vitamin D receptor ligand binding domain complexed with 2MD and a synthetic peptide containing the NR2 box of DRIP 205 分子名称: 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-2-METHYLENE-CYCLOHEXANE-1,3-DIO L, Peroxisome proliferator-activated receptor binding protein, Vitamin D3 receptor 著者 Vanhooke, J.L, Benning, M.M, Bauer, C.B, Pike, J.W, DeLuca, H.F. 登録日 2003-11-19 公開日 2004-04-13 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Molecular Structure of the Rat Vitamin D Receptor Ligand Binding Domain Complexed with 2-Carbon-Substituted Vitamin D(3) Hormone Analogues and a LXXLL-Containing Coactivator Peptide Biochemistry, 43, 2004
1RK3	crystal structure of the rat vitamin D receptor ligand binding domain complexed with 1,25-dihydroxyvitamin D3 and a synthetic peptide containing the NR2 box of DRIP 205 分子名称: 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, Peroxisome proliferator-activated receptor binding protein, Vitamin D3 receptor 著者 Vanhooke, J.L, M Benning, M, Bauer, C.B, Pike, J.W, DeLuca, H.F. 登録日 2003-11-20 公開日 2004-04-13 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Molecular Structure of the Rat Vitamin D Receptor Ligand Binding Domain Complexed with 2-Carbon-Substituted Vitamin D(3) Hormone Analogues and a LXXLL-Containing Coactivator Peptide Biochemistry, 43, 2004
1RKH	crystal structure of the rat vitamin D receptor ligand binding domain complexed with 2AM20R and a synthetic peptide containing the NR2 box of DRIP 205 分子名称: 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-2-METHYL-CYCLOHEXANE-1,3-DIOL, Peroxisome proliferator-activated receptor binding protein, Vitamin D3 receptor 著者 Vanhooke, J.L, Benning, M.M, Bauer, C.B, Pike, J.W, F DeLuca, H. 登録日 2003-11-21 公開日 2004-04-13 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Molecular Structure of the Rat Vitamin D Receptor Ligand Binding Domain Complexed with 2-Carbon-Substituted Vitamin D(3) Hormone Analogues and a LXXLL-Containing Coactivator Peptide Biochemistry, 43, 2004
1RKG	crystal structure of the rat vitamin D receptor ligand binding domain complexed with 2MbisP and a synthetic peptide containing the NR2 box of DRIP 205 分子名称: 5-{2-[1-(1-METHYL-PROPYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-2-METHYLENE-CYCLOHEXANE-1,3-DIOL, Peroxisome proliferator-activated receptor binding protein, Vitamin D3 receptor 著者 Vanhooke, J.L, Benning, M.M, Bauer, C.B, Pike, J.W, DeLuca, H.F. 登録日 2003-11-21 公開日 2004-04-13 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular Structure of the Rat Vitamin D Receptor Ligand Binding Domain Complexed with 2-Carbon-Substituted Vitamin D(3) Hormone Analogues and a LXXLL-Containing Coactivator Peptide Biochemistry, 43, 2004
1S0Z	Crystal structure of the VDR LBD complexed to seocalcitol. 分子名称: SEOCALCITOL, Vitamin D3 receptor 著者 Tocchini-Valentini, G, Rochel, N, Wurtz, J.M, Moras, D. 登録日 2004-01-05 公開日 2004-04-13 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification. J.Med.Chem., 47, 2004
1S0X	Crystal structure of the human RORalpha ligand binding domain in complex with cholesterol sulfate at 2.2A 分子名称: CHOLEST-5-EN-3-YL HYDROGEN SULFATE, Nuclear receptor ROR-alpha 著者 Kallen, J, Schlaeppi, J.M, Bitsch, F, Delhon, I, Fournier, B. 登録日 2004-01-05 公開日 2004-02-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of the human RORalpha Ligand binding domain in complex with cholesterol sulfate at 2.2 A J.Biol.Chem., 279, 2004
1S19	Crystal structure of VDR ligand binding domain complexed to calcipotriol. 分子名称: CALCIPOTRIOL, Vitamin D3 receptor 著者 Tocchini-Valentini, G, Rochel, N, Wurtz, J.M, Moras, D. 登録日 2004-01-06 公開日 2004-04-13 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification. J.Med.Chem., 47, 2004
1VJB	crystal structure of the ligand-binding domain of the estrogen-related receptor gamma in complex with 4-hydroxytamoxifen 分子名称: 4-HYDROXYTAMOXIFEN, Estrogen-related receptor gamma 著者 Greschik, H, Flaig, R, Renaud, J.P, Moras, D. 登録日 2004-02-03 公開日 2004-06-08 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural Basis for the Deactivation of the Estrogen-related Receptor {gamma} by Diethylstilbestrol or 4-Hydroxytamoxifen and Determinants of Selectivity. J.Biol.Chem., 279, 2004
1S9P	crystal structure of the ligand-binding domain of the estrogen-related receptor gamma in complex with diethylstilbestrol 分子名称: DIETHYLSTILBESTROL, Estrogen-related receptor gamma 著者 Greschik, H, Flaig, R, Renaud, J.P, Moras, D. 登録日 2004-02-05 公開日 2004-06-08 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Structural Basis for the Deactivation of the Estrogen-related Receptor {gamma} by Diethylstilbestrol or 4-Hydroxytamoxifen and Determinants of Selectivity. J.Biol.Chem., 279, 2004
1S9Q	crystal structure of the ligand-binding domain of the estrogen-related receptor gamma in complex with 4-hydroxytamoxifen 分子名称: 4-HYDROXYTAMOXIFEN, CHOLIC ACID, Estrogen-related receptor gamma 著者 Greschik, H, Flaig, R, Renaud, J.P, Moras, D. 登録日 2004-02-05 公開日 2004-06-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Basis for the Deactivation of the Estrogen-related Receptor {gamma} by Diethylstilbestrol or 4-Hydroxytamoxifen and Determinants of Selectivity. J.Biol.Chem., 279, 2004
1SJ0	Human Estrogen Receptor Alpha Ligand-binding Domain in Complex with the Antagonist Ligand 4-D 分子名称: (2S,3R)-2-(4-(2-(PIPERIDIN-1-YL)ETHOXY)PHENYL)-2,3-DIHYDRO-3-(4-HYDROXYPHENYL)BENZO[B][1,4]OXATHIIN-6-OL, Estrogen receptor 著者 Kim, S, Wu, J.Y, Birzin, E.T, Chan, W, Pai, L.Y, Yang, Y.T, Mosley, R.T, Fitzgerald, P.M, Sharma, N, DiNinno, F, Rohrer, S.P, Schaeffer, J.M, Hammond, M.L. 登録日 2004-03-02 公開日 2004-04-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Estrogen Receptor Ligands. II. Discovery of Benzoxathiins as Potent, Selective Estrogen Receptor alpha Modulators. J.Med.Chem., 47, 2004
1SKX	Structural Disorder in the Complex of Human PXR and the Macrolide Antibiotic Rifampicin 分子名称: Orphan nuclear receptor PXR, RIFAMPICIN 著者 Chrencik, J.E, Xue, Y, Orans, J.O, Redinbo, M.R. 登録日 2004-03-05 公開日 2005-03-08 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural disorder in the complex of human pregnane x receptor and the macrolide antibiotic rifampicin Mol.Endocrinol., 19, 2005
1SQN	Progesterone Receptor Ligand Binding Domain with bound Norethindrone 分子名称: (14beta,17alpha)-17-ethynyl-17-hydroxyestr-4-en-3-one, progesterone receptor 著者 Williams, S.P, Madauss, K.P, Deng, J.-S, Austin, R.J.H, Lambert, M.H, McLay, I, Pritchard, J, Short, S.A, Stewart, E.L, Uings, I.J. 登録日 2004-03-19 公開日 2004-07-27 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.451 Å) 主引用文献 Progesterone receptor ligand binding pocket flexibility: crystal structures of the norethindrone and mometasone furoate complexes J.Med.Chem., 47, 2004
1SR7	Progesterone Receptor Hormone Binding Domain with Bound Mometasone Furoate 分子名称: GLYCEROL, MOMETASONE FUROATE, Progesterone receptor, ... 著者 Madauss, K.P, Deng, S.-J, Austin, R.J, Lambert, M.H, McLay, I, Pritchard, J, Short, S.A, Stewart, E.L, Uings, I.J, Williams, S.P. 登録日 2004-03-22 公開日 2004-06-22 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Progesterone receptor ligand binding pocket flexibility: crystal structures of the norethindrone and mometasone furoate complexes J.Med.Chem., 47, 2004
1T65	Crystal structure of the androgen receptor ligand binding domain with DHT and a peptide derived form its physiological coactivator GRIP1 NR box 2 bound in a non-helical conformation 分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, Nuclear receptor coactivator 2 著者 Estebanez-Perpina, E, Moore, J.M.R, Mar, E, Nguyen, P, Delgado-Rodrigues, E, Baxter, J.D, Webb, P, Fletterick, R.J, Guy, R.K. 登録日 2004-05-05 公開日 2005-01-25 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 The Molecular Mechanisms of Coactivator Utilization in Ligand-dependent Transactivation by the Androgen Receptor. J.Biol.Chem., 280, 2005
1T5Z	Crystal Structure of the Androgen Receptor Ligand Binding Domain (LBD) with DHT and a peptide derived from its physiological coactivator ARA70 分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, Nuclear receptor coactivator 4 著者 Estebanez-Perpina, E, Moore, J.M.R, Mar, E, Nguyen, P, Delgado-Rodrigues, E, Baxter, J.D, Webb, P, Fletterick, R.J, Guy, R.K. 登録日 2004-05-05 公開日 2005-01-25 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Molecular Mechanisms of Coactivator Utilization in Ligand-dependent Transactivation by the Androgen Receptor. J.Biol.Chem., 280, 2005
1T63	Crystal Structure of the Androgen Receptor Ligand Binding Domain with DHT and a peptide derived from its physiological coactivator GRIP1 NR box3 分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, Nuclear receptor coactivator 2 著者 Estebanez-Perpina, E, Moore, J.M.R, Mar, E, Nguyen, P, Delgado-Rodrigues, E, Baxter, J.D, Webb, P, Fletterick, R.J, Guy, R.K. 登録日 2004-05-05 公開日 2005-01-25 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 The Molecular Mechanisms of Coactivator Utilization in Ligand-dependent Transactivation by the Androgen Receptor. J.Biol.Chem., 280, 2005
1T74	Crystal structure of the androgen receptor ligand binding domain in complex with a WxxLF motif 分子名称: 1,2-ETHANEDIOL, 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, ... 著者 Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J. 登録日 2004-05-07 公開日 2004-08-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Recognition and accommodation at the androgen receptor coactivator binding interface. Plos Biol., 2, 2004
1T73	Crystal structure of the androgen receptor ligand binding domain in complex with a FxxFF motif 分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, FxxFF motif peptide, ... 著者 Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J. 登録日 2004-05-07 公開日 2004-08-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Recognition and accommodation at the androgen receptor coactivator binding interface. Plos Biol., 2, 2004
1T76	Crystal structure of the androgen receptor ligand binding domain in complex with a WxxVW motif 分子名称: 1,2-ETHANEDIOL, 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, ... 著者 Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J. 登録日 2004-05-08 公開日 2004-08-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Recognition and accommodation at the androgen receptor coactivator binding interface. Plos Biol., 2, 2004
1T79	Crystal structure of the androgen receptor ligand binding domain in complex with a FxxLW motif 分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, FxxLW motif peptide 著者 Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J. 登録日 2004-05-08 公開日 2004-08-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Recognition and accommodation at the androgen receptor coactivator binding interface. Plos Biol., 2, 2004

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