1S9Q
crystal structure of the ligand-binding domain of the estrogen-related receptor gamma in complex with 4-hydroxytamoxifen
Summary for 1S9Q
Entry DOI | 10.2210/pdb1s9q/pdb |
Related | 1KV6 1S9P |
Descriptor | Estrogen-related receptor gamma, 4-HYDROXYTAMOXIFEN, CHOLIC ACID, ... (4 entities in total) |
Functional Keywords | ligand-binding domain, antagonist complex, transcription |
Biological source | Mus musculus (house mouse) |
Cellular location | Nucleus (Probable): P62509 |
Total number of polymer chains | 2 |
Total formula weight | 58366.06 |
Authors | Greschik, H.,Flaig, R.,Renaud, J.P.,Moras, D. (deposition date: 2004-02-05, release date: 2004-06-08, Last modification date: 2023-09-20) |
Primary citation | Greschik, H.,Flaig, R.,Renaud, J.P.,Moras, D. Structural Basis for the Deactivation of the Estrogen-related Receptor {gamma} by Diethylstilbestrol or 4-Hydroxytamoxifen and Determinants of Selectivity. J.Biol.Chem., 279:33639-33646, 2004 Cited by PubMed: 15161930DOI: 10.1074/jbc.M402195200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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