1S9Q

crystal structure of the ligand-binding domain of the estrogen-related receptor gamma in complex with 4-hydroxytamoxifen

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Estrogen-related receptor gamma	polymer	251	28386.9	2	UniProt (P62509) Pfam (PF00104) In PDB	Mus musculus (house mouse)	Estrogen receptor related protein 3, ERR gamma-2
2	A, B	4-HYDROXYTAMOXIFEN	non-polymer		387.5	2	Chemie (OHT)
3	A, B	CHOLIC ACID	non-polymer		408.6	2	Chemie (CHD)
4		water	water		18.0	124	Chemie (HOH)

Sequence modifications

A, B: 229 - 458 (UniProt: P62509)

PDB	External Database	Details
Met 208	-	cloning artifact
Gly 209	-	cloning artifact
Ser 210	-	cloning artifact
Ser 211	-	cloning artifact
His 212	-	expression tag
His 213	-	expression tag
His 214	-	expression tag
His 215	-	expression tag
His 216	-	expression tag
His 217	-	expression tag
Ser 218	-	cloning artifact
Ser 219	-	cloning artifact
Gly 220	-	cloning artifact
Leu 221	-	cloning artifact
Val 222	-	cloning artifact
Pro 223	-	cloning artifact
Arg 224	-	cloning artifact
Gly 225	-	cloning artifact
Ser 226	-	cloning artifact
His 227	-	cloning artifact
Met 228	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56773.9
Non-Polymers*	Number of molecules	4
	Total formula weight	1592.2
All*	Total formula weight	58366.1

*Water molecules are not included.