1S9Q
crystal structure of the ligand-binding domain of the estrogen-related receptor gamma in complex with 4-hydroxytamoxifen
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Estrogen-related receptor gamma | polymer | 251 | 28386.9 | 2 | UniProt (P62509) Pfam (PF00104) | Mus musculus (house mouse) | Estrogen receptor related protein 3, ERR gamma-2 |
| 2 | C, E (A, B) | 4-HYDROXYTAMOXIFEN | non-polymer | 387.5 | 2 | Chemie (OHT) | |||
| 3 | D, F (A, B) | CHOLIC ACID | non-polymer | 408.6 | 2 | Chemie (CHD) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 124 | Chemie (HOH) |
Sequence modifications
A, B: 229 - 458 (UniProt: P62509)
| PDB | External Database | Details |
|---|---|---|
| Met 208 | - | cloning artifact |
| Gly 209 | - | cloning artifact |
| Ser 210 | - | cloning artifact |
| Ser 211 | - | cloning artifact |
| His 212 | - | expression tag |
| His 213 | - | expression tag |
| His 214 | - | expression tag |
| His 215 | - | expression tag |
| His 216 | - | expression tag |
| His 217 | - | expression tag |
| Ser 218 | - | cloning artifact |
| Ser 219 | - | cloning artifact |
| Gly 220 | - | cloning artifact |
| Leu 221 | - | cloning artifact |
| Val 222 | - | cloning artifact |
| Pro 223 | - | cloning artifact |
| Arg 224 | - | cloning artifact |
| Gly 225 | - | cloning artifact |
| Ser 226 | - | cloning artifact |
| His 227 | - | cloning artifact |
| Met 228 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 56773.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1592.2 | |
| All* | Total formula weight | 58366.1 |
