1T79

Crystal structure of the androgen receptor ligand binding domain in complex with a FxxLW motif

Summary for 1T79

Related1T73 1T74 1T76 1T7F 1T7M 1T7R 1T7T
DescriptorAndrogen receptor, FxxLW motif peptide, 5-ALPHA-DIHYDROTESTOSTERONE, ... (4 entities in total)
Functional Keywordsnuclear receptor, transcription factor, ligand binding domain, af-2, androgen, testosterone, dht, alpha-helical sandwich, hormone-growth factor receptor complex, hormone/growth factor receptor
Biological sourcePan troglodytes (chimpanzee)
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Cellular locationNucleus (By similarity) O97775
Total number of polymer chains2
Total molecular weight33291.81
Authors
Hur, E.,Pfaff, S.J.,Payne, E.S.,Gron, H.,Buehrer, B.M.,Fletterick, R.J. (deposition date: 2004-05-08, release date: 2004-08-31, Last modification date: 2011-07-13)
Primary citation
Hur, E.,Pfaff, S.J.,Payne, E.S.,Gron, H.,Buehrer, B.M.,Fletterick, R.J.
Recognition and accommodation at the androgen receptor coactivator binding interface.
Plos Biol., 2:E274-E274, 2004
PubMed: 15328534 (PDB entries with the same primary citation)
DOI: 10.1371/journal.pbio.0020274
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.21730 0.4% 1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
170172
PDB entries from 2020-10-21