1T79
Crystal structure of the androgen receptor ligand binding domain in complex with a FxxLW motif
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Androgen receptor | polymer | 269 | 30878.0 | 1 | UniProt (O97775) Pfam (PF00104) | Pan troglodytes (chimpanzee) | Dihydrotestosterone receptor |
| 2 | B (B) | FxxLW motif peptide | polymer | 20 | 2123.4 | 1 | |||
| 3 | C (A) | 5-ALPHA-DIHYDROTESTOSTERONE | non-polymer | 290.4 | 1 | Chemie (DHT) PubChem (1779160) PubChem (15) PubChem (10635) PubChem (147320) PubChem (667503) PubChem (928651) PubChem (6432518) PubChem (7052570) PubChem (7052571) PubChem (9965809) PubChem (10379482) PubChem (10902374) PubChem (11860392) PubChem (11867857) PubChem (11867858) PubChem (11867859) PubChem (11867860) PubChem (11869358) PubChem (11869359) PubChem (11869361) PubChem (11914201) PubChem (11920866) PubChem (12446746) PubChem (12446747) PubChem (12446748) PubChem (12446749) PubChem (12446752) PubChem (16395945) PubChem (23729584) PubChem (44264584) PubChem (44307156) PubChem (44308180) PubChem (44314545) PubChem (1779165) PubChem (1779163) PubChem (44403751) PubChem (57253355) PubChem (2748143) PubChem (11302) PubChem (968803) PubChem (54132599) PubChem (6951009) PubChem (124916763) PubChem (133612463) PubChem (11869360) PubChem (16111632) PubChem (67080676) PubChem (68213431) PubChem (70627790) PubChem (76333143) PubChem (90350225) PubChem (124305346) PubChem (124335861) PubChem (124350819) PubChem (124362930) PubChem (124402106) PubChem (124420348) PubChem (124907326) PubChem (124907327) PubChem (134753818) PubChem (139564330) PubChem (141909893) PubChem (142776876) PubChem (145087815) PubChem (156740897) PubChem (162854571) PubChem (162854572) PubChem (162854573) PubChem (164663566) PubChem (165146196) PubChem (165431280) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 145 | Chemie (HOH) |
Sequence modifications
A: 662 - 919 (UniProt: O97775)
| PDB | External Database | Details |
|---|---|---|
| Gly 651 | - | cloning artifact |
| Ser 652 | - | cloning artifact |
| Pro 653 | - | cloning artifact |
| Gly 654 | - | cloning artifact |
| Ile 655 | - | cloning artifact |
| Ser 656 | - | cloning artifact |
| Gly 657 | - | cloning artifact |
| Gly 658 | - | cloning artifact |
| Gly 659 | - | cloning artifact |
| Gly 660 | - | cloning artifact |
| Gly 661 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33001.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 290.4 | |
| All* | Total formula weight | 33291.8 |
