PDB: 35140 件ウェブページステータス検索Chemie searchBIRD

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4QSL	Crystal Structure of Listeria Monocytogenes Pyruvate Carboxylase 分子名称: Pyruvate carboxylase 著者 Choi, P.H, Tong, L. 登録日 2014-07-04 公開日 2014-10-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.28 Å) 主引用文献 The Cyclic Dinucleotide c-di-AMP Is an Allosteric Regulator of Metabolic Enzyme Function. Cell(Cambridge,Mass.), 158, 2014
8CVT	Human 19S-20S proteasome, state SD2 分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... 著者 Zhao, J. 登録日 2022-05-18 公開日 2022-11-02 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins. Proc.Natl.Acad.Sci.USA, 119, 2022
7TV4	Crystal structure of NEMO CoZi in complex with HOIP NZF1 and linear diubiquitin 分子名称: E3 ubiquitin-protein ligase RNF31, NF-kappa-B essential modulator, Polyubiquitin-C, ... 著者 Rahighi, S, Iyer, M, Oveisi, H. 登録日 2022-02-03 公開日 2022-08-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Structural basis for the simultaneous recognition of NEMO and acceptor ubiquitin by the HOIP NZF1 domain. Sci Rep, 12, 2022
7TR4	MA2-MART1-HLAA0201 分子名称: Beta-2-microglobulin, GLYCEROL, HLA-A*02:01, ... 著者 Yang, X, Jude, K.M, Garcia, K.C. 登録日 2022-01-27 公開日 2022-11-23 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Facile repurposing of peptide-MHC-restricted antibodies for cancer immunotherapy. Nat.Biotechnol., 41, 2023
5C5Q	CRYSTAL STRUCTURE OF HUMAN TANKYRASE-2 IN COMPLEX WITH A PYRANOPYRIDONE INHIBITOR 分子名称: (3R)-10-methyl-3-(propan-2-yl)-1,3,4,5-tetrahydro-6H-pyrano[4,3-c]isoquinolin-6-one, SULFATE ION, Tankyrase-2, ... 著者 Lukacs, C.M, Janson, C.A. 登録日 2015-06-21 公開日 2015-08-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Fragment-Based Drug Design of Novel Pyranopyridones as Cell Active and Orally Bioavailable Tankyrase Inhibitors. Acs Med.Chem.Lett., 6, 2015
7W0S	TRIM7 in complex with C-terminal peptide of 2C 分子名称: DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase TRIM7, GLYCEROL, ... 著者 Zhang, H, Liang, X, Li, X.Z. 登録日 2021-11-18 公開日 2022-08-10 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures. Nat.Chem.Biol., 18, 2022
5YR0	Structure of Beclin1-UVRAG coiled coil domain complex 分子名称: Beclin-1, UV radiation resistance associated protein 著者 Pan, X, Zhao, Y, He, Y. 登録日 2017-11-08 公開日 2018-06-13 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Targeting the potent Beclin 1-UVRAG coiled-coil interaction with designed peptides enhances autophagy and endolysosomal trafficking. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7W0Q	TRIM7 in complex with C-terminal peptide of 2C 分子名称: E3 ubiquitin-protein ligase TRIM7, peptide 著者 Zhang, H, Liang, X, Li, X.Z. 登録日 2021-11-18 公開日 2022-08-10 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures. Nat.Chem.Biol., 18, 2022
7W0T	TRIM7 in complex with C-terminal peptide of 2C 分子名称: E3 ubiquitin-protein ligase TRIM7, peptide 著者 Zhang, H, Liang, X, Li, X.Z. 登録日 2021-11-18 公開日 2022-08-10 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures. Nat.Chem.Biol., 18, 2022
5XYY	The structure of p38 alpha in complex with a triazol inhibitor 分子名称: 3-(5-{[(2-chloro-6-fluorophenyl)methyl]amino}-4H-1,2,4-triazol-3-yl)phenol, Mitogen-activated protein kinase 14 著者 Wang, Y.L, Sun, Y.Z, Cao, R, Liu, D, Li, L, Qi, X.B, Huang, N. 登録日 2017-07-11 公開日 2018-01-17 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 In Silico Identification of a Novel Hinge-Binding Scaffold for Kinase Inhibitor Discovery. J. Med. Chem., 60, 2017
7AJ0	Crystal structure of PsFucS1 sulfatase from Pseudoalteromonas sp. 分子名称: Arylsulfatase, CALCIUM ION, CHLORIDE ION 著者 Roret, T, Mikkelsen, M.D, Czjzek, M, Meyer, A.S. 登録日 2020-09-28 公開日 2021-09-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A novel thermostable prokaryotic fucoidan active sulfatase PsFucS1 with an unusual quaternary hexameric structure. Sci Rep, 11, 2021
4M7B	Human tankyrase 2 - catalytic Parp domain in complex with an inhibitor UPF1854 分子名称: 4-{2-[(6-methyl[1,2,4]triazolo[4,3-b]pyridazin-8-yl)amino]ethyl}phenol, SULFATE ION, Tankyrase-2, ... 著者 Karlberg, T, Camaioni, E, Schuler, H. 登録日 2013-08-12 公開日 2014-03-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Design, Synthesis, Crystallographic Studies, and Preliminary Biological Appraisal of New Substituted Triazolo[4,3-b]pyridazin-8-amine Derivatives as Tankyrase Inhibitors. J.Med.Chem., 57, 2014
3FEY	Crystal structure of the CBC-importin alpha complex. 分子名称: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2 著者 Dias, S.M.G, Ambrosio, A.L.B, Cerione, R.A. 登録日 2008-12-01 公開日 2009-08-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The molecular basis for the regulation of the cap-binding complex by the importins. Nat.Struct.Mol.Biol., 16, 2009
3FI4	P38 kinase crystal structure in complex with RO4499 分子名称: (2S)-1-{[3-(2-chlorophenyl)-6-(2,4-difluorophenoxy)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}propan-2-ol, Mitogen-activated protein kinase 14 著者 Kuglstatter, A, Knapp, M, Dunten, P. 登録日 2008-12-10 公開日 2009-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Mapping Binding Pocket Volume: Potential Applications towards Ligand Design and Selectivity To be Published
5JLE	Crystal structure of SETD2 bound to SAH 分子名称: Histone-lysine N-methyltransferase SETD2, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION 著者 Li, H, Yang, S, Zheng, X. 登録日 2016-04-27 公開日 2016-11-02 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular basis for oncohistone H3 recognition by SETD2 methyltransferase Genes Dev., 30, 2016
3FMN	P38 kinase crystal structure in complex with RO2530 分子名称: 6-(2,4-difluorophenoxy)-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-amine, Mitogen-activated protein kinase 14 著者 Kuglstatter, A, Ghate, M. 登録日 2008-12-22 公開日 2009-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 P38 kinase crystal structure in complex with RO2530 To be Published
4Z8L	Crystal structure of DCAF1/SIV-MND VPX/MND SAMHD1 NTD ternary complex 分子名称: Protein VPRBP, SAM domain and HD domain-containing protein, Vpx protein, ... 著者 Koharudin, L.M, Wu, Y, Calero, G, Ahn, J, Gronenborn, A.M. 登録日 2015-04-09 公開日 2015-06-17 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Basis of Clade-specific Engagement of SAMHD1 (Sterile alpha Motif and Histidine/Aspartate-containing Protein 1) Restriction Factors by Lentiviral Viral Protein X (Vpx) Virulence Factors. J.Biol.Chem., 290, 2015
7UNZ	Crystal structure of H2 nanobody in complex with PfCSS 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Scally, S.W, Cowman, A.F. 登録日 2022-04-12 公開日 2022-11-23 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 PCRCR complex is essential for invasion of human erythrocytes by Plasmodium falciparum. Nat Microbiol, 7, 2022
4Z4M	Crystal structure of GFP-TAX1BP1 UBZ2 domain fusion protein 分子名称: Green fluorescent protein,Tax1-binding protein 1, ZINC ION 著者 Rohaim, A, Kawasaki, M, Wakatsuki, S. 登録日 2015-04-02 公開日 2016-04-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 A novel mode of ubiquitin recognition by the ubiquitin-binding zinc finger domain of WRNIP1. Febs J., 283, 2016
4L0Z	Crystal structure of Runx1 and Ets1 bound to TCR alpha promoter (crystal form 2) 分子名称: 5'-D(*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3', 5'-D(*GP*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3', Protein C-ets-1, ... 著者 Tahirov, T.H. 登録日 2013-06-01 公開日 2014-03-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis of Ets1 activation by Runx1. Leukemia, 28, 2014
7UNY	Crystal structure of D2 nanobody in complex with PfCSS 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cysteine-rich small secreted protein CSS, ... 著者 Scally, S.W, Lim, P.S, Cowman, A.F. 登録日 2022-04-12 公開日 2022-11-23 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (4.13 Å) 主引用文献 PCRCR complex is essential for invasion of human erythrocytes by Plasmodium falciparum. Nat Microbiol, 7, 2022
4L39	Crystal structure of GH3.12 from Arabidopsis thaliana in complex with AMPCPP and salicylate 分子名称: 2-HYDROXYBENZOIC ACID, 4-substituted benzoates-glutamate ligase GH3.12, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... 著者 Zubieta, C, Jez, J.M, Brown, E, Marcellin, R, Kapp, U, Round, A, Westfall, C. 登録日 2013-06-05 公開日 2013-10-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 Determination of the GH3.12 protein conformation through HPLC-integrated SAXS measurements combined with X-ray crystallography. Acta Crystallogr.,Sect.D, 69, 2013
4ZGZ	STRUCTURE OF HUMAN ANTIZYME INHIBITOR IN COMPLEX WITH A C-TERMINAL FRAGMENT OF ANTIZYME 分子名称: Antizyme inhibitor 1, Ornithine decarboxylase antizyme 1 著者 Chen, S.F, Wu, H.Y, Chan, N.L. 登録日 2015-04-24 公開日 2015-09-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (5.81 Å) 主引用文献 Structural basis of antizyme-mediated regulation of polyamine homeostasis Proc.Natl.Acad.Sci.USA, 112, 2015
4ZHI	Eg5 motor domain mutant E162S 分子名称: ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11 著者 Luo, M, Park, C, Worthylake, D, Kim, S. 登録日 2015-04-24 公開日 2016-06-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Eg5 To Be Published
4L33	Tankyrase 2 in complex with cyanomethyl 4-(4-oxo-4H-chromen-2-yl)benzoate 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, SULFATE ION, ... 著者 Narwal, M, Haikarainen, T, Lehtio, L. 登録日 2013-06-05 公開日 2013-10-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity. J.Med.Chem., 56, 2013

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