4ZGZ
STRUCTURE OF HUMAN ANTIZYME INHIBITOR IN COMPLEX WITH A C-TERMINAL FRAGMENT OF ANTIZYME
Summary for 4ZGZ
Entry DOI | 10.2210/pdb4zgz/pdb |
Related | 1ZO0 3BTN 4QCG |
Descriptor | Antizyme inhibitor 1, Ornithine decarboxylase antizyme 1 (2 entities in total) |
Functional Keywords | tim barrel domain, beta-sheet domain, inhibition, antizyme, plasma, protein binding |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : O14977 |
Total number of polymer chains | 4 |
Total formula weight | 126499.04 |
Authors | Chen, S.F.,Wu, H.Y.,Chan, N.L. (deposition date: 2015-04-24, release date: 2015-09-02, Last modification date: 2023-11-29) |
Primary citation | Wu, H.Y.,Chen, S.F.,Hsieh, J.Y.,Chou, F.,Wang, Y.H.,Lin, W.T.,Lee, P.Y.,Yu, Y.J.,Lin, L.Y.,Lin, T.S.,Lin, C.L.,Liu, G.Y.,Tzeng, S.R.,Hung, H.C.,Chan, N.L. Structural basis of antizyme-mediated regulation of polyamine homeostasis Proc.Natl.Acad.Sci.USA, 112:11229-11234, 2015 Cited by PubMed: 26305948DOI: 10.1073/pnas.1508187112 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (5.81 Å) |
Structure validation
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