4ZGZ

STRUCTURE OF HUMAN ANTIZYME INHIBITOR IN COMPLEX WITH A C-TERMINAL FRAGMENT OF ANTIZYME

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Antizyme inhibitor 1	polymer	438	48470.8	2	UniProt (O14977) Pfam (PF00278) Pfam (PF02784)	Homo sapiens (Human)	AZI,Ornithine decarboxylase antizyme inhibitor
2	B, D (B, D)	Ornithine decarboxylase antizyme 1	polymer	128	14778.7	2	UniProt (P54368) Pfam (PF02100)	Homo sapiens (Human)	ODC-Az

Sequence modifications

A, C: 2 - 437 (UniProt: O14977)

PDB	External Database	Details
Met 0	-	initiating methionine
Gly 1	-	expression tag
Asp 20	Asn 20	engineered mutation

B, D: 110 - 228 (UniProt: P54368)

PDB	External Database	Details
Met 109	-	initiating methionine
Leu 229	-	expression tag
Glu 230	-	expression tag
His 231	-	expression tag
His 232	-	expression tag
His 233	-	expression tag
His 234	-	expression tag
His 235	-	expression tag
His 236	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	126499.0
All*	Total formula weight	126499.0

*Water molecules are not included.