4ZGZ

STRUCTURE OF HUMAN ANTIZYME INHIBITOR IN COMPLEX WITH A C-TERMINAL FRAGMENT OF ANTIZYME

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004586	molecular_function	ornithine decarboxylase activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006596	biological_process	polyamine biosynthetic process
A	0033387	biological_process	putrescine biosynthetic process from ornithine
A	0042177	biological_process	negative regulation of protein catabolic process
A	0042978	molecular_function	ornithine decarboxylase activator activity
A	1902269	biological_process	positive regulation of polyamine transmembrane transport
B	0008073	molecular_function	ornithine decarboxylase inhibitor activity
C	0003824	molecular_function	catalytic activity
C	0004586	molecular_function	ornithine decarboxylase activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006596	biological_process	polyamine biosynthetic process
C	0033387	biological_process	putrescine biosynthetic process from ornithine
C	0042177	biological_process	negative regulation of protein catabolic process
C	0042978	molecular_function	ornithine decarboxylase activator activity
C	1902269	biological_process	positive regulation of polyamine transmembrane transport
D	0008073	molecular_function	ornithine decarboxylase inhibitor activity

Functional Information from PROSITE/UniProt

site_id	PS00879
Number of Residues	18
Details	ODR_DC_2_2 Orn/DAP/Arg decarboxylases family 2 signature 2. AgeigftMnMLDIGGGFT

Chain	Residue	Details
A	ALA222-THR239

site_id	PS01337
Number of Residues	9
Details	ODC_AZ Ornithine decarboxylase antizyme signature. LLEFAEEQL

Chain	Residue	Details
B	LEU159-LEU167

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	SITE: Not modified => ECO:0000250\|UniProtKB:O35484