7TV4

Crystal structure of NEMO CoZi in complex with HOIP NZF1 and linear diubiquitin

Summary for 7TV4

• Entry DOI: 10.2210/pdb7tv4/pdb
• Descriptor: NF-kappa-B essential modulator, Polyubiquitin-C, E3 ubiquitin-protein ligase RNF31, ... (5 entities in total)
• Functional Keywords: signaling protein, ubiquitin signaling, nf-kappa b signaling
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 61229.16

Authors

Rahighi, S.,Iyer, M.,Oveisi, H. (deposition date: 2022-02-03, release date: 2022-08-17, Last modification date: 2023-10-18)

• Primary citation: Rahighi, S.,Iyer, M.,Oveisi, H.,Nasser, S.,Duong, V.; Structural basis for the simultaneous recognition of NEMO and acceptor ubiquitin by the HOIP NZF1 domain.; Sci Rep, 12:12241-12241, 2022; PubMed: 35851409; DOI: 10.1038/s41598-022-16193-4

Experimental method

X-RAY DIFFRACTION (4.2 Å)