5JLE

Crystal structure of SETD2 bound to SAH

Summary for 5JLE

• Entry DOI: 10.2210/pdb5jle/pdb
• Related: 5JJY 5JLB
• Descriptor: Histone-lysine N-methyltransferase SETD2, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total)
• Functional Keywords: set domain, transferase
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : Q9BYW2
• Total number of polymer chains: 1
• Total formula weight: 32623.21

Authors

Li, H.,Yang, S.,Zheng, X. (deposition date: 2016-04-27, release date: 2016-11-02, Last modification date: 2023-11-08)

• Primary citation: Yang, S.,Zheng, X.,Lu, C.,Li, G.M.,Allis, C.D.,Li, H.; Molecular basis for oncohistone H3 recognition by SETD2 methyltransferase; Genes Dev., 30:1611-1616, 2016; PubMed: 27474439; DOI: 10.1101/gad.284323.116

Experimental method

X-RAY DIFFRACTION (2.4 Å)