7UNY

Crystal structure of D2 nanobody in complex with PfCSS

Summary for 7UNY

• Entry DOI: 10.2210/pdb7uny/pdb
• Descriptor: Cysteine-rich small secreted protein CSS, D2 Nanobody, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: 6-cys protein, nanobody, cell invasion
• Biological source: Plasmodium falciparum (malaria parasite P. falciparum); More
• Total number of polymer chains: 4
• Total formula weight: 99824.54

Authors

Scally, S.W.,Lim, P.S.,Cowman, A.F. (deposition date: 2022-04-12, release date: 2022-11-23, Last modification date: 2023-10-25)

• Primary citation: Scally, S.W.,Triglia, T.,Evelyn, C.,Seager, B.A.,Pasternak, M.,Lim, P.S.,Healer, J.,Geoghegan, N.D.,Adair, A.,Tham, W.H.,Dagley, L.F.,Rogers, K.L.,Cowman, A.F.; PCRCR complex is essential for invasion of human erythrocytes by Plasmodium falciparum.; Nat Microbiol, 7:2039-2053, 2022; PubMed: 36396942; DOI: 10.1038/s41564-022-01261-2

Experimental method

X-RAY DIFFRACTION (4.13 Å)