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PDB: 25 results

7LXR
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Kinesin-like protein at 61F (Klp61f) bound to AMPPNP
Descriptor: 1,2-ETHANEDIOL, IODIDE ION, Kinesin-like protein Klp61F, ...
Authors:Worthylake, D.K, Wojcik, E.J.
Deposit date:2021-03-04
Release date:2022-11-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.744 Å)
Cite:Crystal Structure of the Klp61f motor domain bound to AMPPNP
To Be Published
1A43
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STRUCTURE OF THE HIV-1 CAPSID PROTEIN DIMERIZATION DOMAIN AT 2.6A RESOLUTION
Descriptor: HIV-1 CAPSID
Authors:Worthylake, D.K, Wang, H, Yoo, S, Sundquist, W.I, Hill, C.P.
Deposit date:1998-02-10
Release date:1999-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of the HIV-1 capsid protein dimerization domain at 2.6 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
1BAJ
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BU of 1baj by Molmil
HIV-1 CAPSID PROTEIN C-TERMINAL FRAGMENT PLUS GAG P2 DOMAIN
Descriptor: GAG POLYPROTEIN
Authors:Worthylake, D.K, Wang, H, Yoo, S, Sundquist, W.I, Hill, C.P.
Deposit date:1998-04-17
Release date:1998-10-14
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of the HIV-1 capsid protein dimerization domain at 2.6 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
5CJP
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BU of 5cjp by Molmil
The Structural Basis for Cdc42-Induced Dimerization of IQGAPs
Descriptor: Cell division cycle 42 (GTP binding protein, 25kDa), isoform CRA_a, ...
Authors:Worthylake, D.K, Boyapati, V.K, LeCour Jr, L.
Deposit date:2015-07-14
Release date:2016-08-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Structural Basis for Cdc42-Induced Dimerization of IQGAPs.
Structure, 24, 2016
1AYZ
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CRYSTAL STRUCTURE OF THE SACCHAROMYCES CEREVISIAE UBIQUITIN-CONJUGATING ENZYME RAD6 (UBC2) AT 2.6A RESOLUTION
Descriptor: UBIQUITIN-CONJUGATING ENZYME RAD6
Authors:Worthylake, D.K, Prakash, S, Prakash, L, Hill, C.P.
Deposit date:1997-11-12
Release date:1998-08-26
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the Saccharomyces cerevisiae ubiquitin-conjugating enzyme Rad6 at 2.6 A resolution.
J.Biol.Chem., 273, 1998
1RJ2
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BU of 1rj2 by Molmil
Crystal structure of the DH/PH fragment of Dbs without bound GTPase
Descriptor: Guanine nucleotide exchange factor DBS [Fragment]
Authors:Worthylake, D.K, Rossman, K.L, Sondek, J.
Deposit date:2003-11-18
Release date:2004-06-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the DH/PH fragment of Dbs without bound GTPase.
Structure, 12, 2004
1F3G
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BU of 1f3g by Molmil
THREE-DIMENSIONAL STRUCTURE OF THE ESCHERICHIA COLI PHOSPHOCARRIER PROTEIN III GLC
Descriptor: GLUCOSE-SPECIFIC PHOSPHOCARRIER PROTEIN IIAGLC
Authors:Worthylake, D, Meadow, N, Roseman, S, Liao, D.-I, Herzberg, O, Remington, S.J.
Deposit date:1991-08-28
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Three-dimensional structure of the Escherichia coli phosphocarrier protein IIIglc.
Proc.Natl.Acad.Sci.USA, 88, 1991
1FOE
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BU of 1foe by Molmil
CRYSTAL STRUCTURE OF RAC1 IN COMPLEX WITH THE GUANINE NUCLEOTIDE EXCHANGE REGION OF TIAM1
Descriptor: RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE, SULFATE ION, T-LYMPHOMA INVASION AND METASTASIS INDUCING PROTEIN 1
Authors:Worthylake, D.K, Rossman, K.L, Sondek, J.
Deposit date:2000-08-27
Release date:2001-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1.
Nature, 408, 2000
5L0O
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BU of 5l0o by Molmil
IQGAP1 calponin homology domain fragment (CHDF) mutant K161C under oxidizing conditions
Descriptor: Ras GTPase-activating-like protein IQGAP1
Authors:Liu, J, Worthylake, D.
Deposit date:2016-07-27
Release date:2016-09-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:The IQGAP1 N-Terminus Forms Dimers, and the Dimer Interface Is Required for Binding F-Actin and Calcium-Bound Calmodulin.
Biochemistry, 55, 2016
1AUM
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BU of 1aum by Molmil
HIV CAPSID C-TERMINAL DOMAIN (CAC146)
Descriptor: HIV CAPSID
Authors:Hill, C.P, Gamble, T.R, Yoo, S, Vajdos, F.F, Von Schwedler, U.K, Worthylake, D.K, Wang, H, Mccutcheon, J.P, Sundquist, W.I.
Deposit date:1997-08-29
Release date:1998-01-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the carboxyl-terminal dimerization domain of the HIV-1 capsid protein.
Science, 278, 1997
4H20
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Crystal Structure and Computational Modeling of the Fab Fragment from the Protective anti-Ricin Monoclonal Antibody RAC18
Descriptor: Heavy chain of Fab Fragment from the anti-Ricin Monoclonal Antibody RAC18, Light chain of Fab Fragment from the anti-Ricin Monoclonal Antibody RAC18
Authors:Zhao, Z, Worthylake, D.K, LeCour Jr, L.F, Maresh, G, Pincus, S.H.
Deposit date:2012-09-11
Release date:2012-10-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure and computational modeling of the fab fragment from a protective anti-ricin monoclonal antibody.
Plos One, 7, 2012
1AK4
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HUMAN CYCLOPHILIN A BOUND TO THE AMINO-TERMINAL DOMAIN OF HIV-1 CAPSID
Descriptor: CYCLOPHILIN A, HIV-1 CAPSID
Authors:Hill, C.P, Gamble, T.R, Vajdos, F.F, Worthylake, D.K, Sundquist, W.I.
Deposit date:1997-05-28
Release date:1997-10-15
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Crystal structure of human cyclophilin A bound to the amino-terminal domain of HIV-1 capsid.
Cell(Cambridge,Mass.), 87, 1996
1A8O
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HIV CAPSID C-TERMINAL DOMAIN
Descriptor: HIV CAPSID
Authors:Gamble, T.R, Yoo, S, Vajdos, F.F, Von Schwedler, U.K, Worthylake, D.K, Wang, H, Mccutcheon, J.P, Sundquist, W.I, Hill, C.P.
Deposit date:1998-03-27
Release date:1998-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the carboxyl-terminal dimerization domain of the HIV-1 capsid protein.
Science, 278, 1997
3FAY
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BU of 3fay by Molmil
Crystal structure of the GAP-related domain of IQGAP1
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Ras GTPase-activating-like protein IQGAP1
Authors:Kurella, V.B, Richard, J.M, Parke, C.L, Bellamy, H, Worthylake, D.K.
Deposit date:2008-11-18
Release date:2009-03-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the GTPase-activating protein-related domain from IQGAP1.
J.Biol.Chem., 284, 2009
2NZ8
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BU of 2nz8 by Molmil
N-terminal DHPH cassette of Trio in complex with nucleotide-free Rac1
Descriptor: ras-related C3 botulinum toxin substrate 1 isoform Rac1, triple functional domain protein
Authors:Chhatriwala, M.K, Betts, L, Worthylake, D.K, Sondek, J.
Deposit date:2006-11-22
Release date:2007-04-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:The DH and PH Domains of Trio Coordinately Engage Rho GTPases for their Efficient Activation
J.Mol.Biol., 368, 2007
4ZCA
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BU of 4zca by Molmil
Eg5 motor domain mutant Y231F
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, MAGNESIUM ION
Authors:Luo, M, Parke, C, Worthylake, D.
Deposit date:2015-04-15
Release date:2016-06-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Eg5
To Be Published
4ZHI
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BU of 4zhi by Molmil
Eg5 motor domain mutant E162S
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11
Authors:Luo, M, Park, C, Worthylake, D, Kim, S.
Deposit date:2015-04-24
Release date:2016-06-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Eg5
To Be Published
3HQD
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BU of 3hqd by Molmil
Human kinesin Eg5 motor domain in complex with AMPPNP and Mg2+
Descriptor: Kinesin-like protein KIF11, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Parke, C.L, Wojcik, E.J, Kim, S, Worthylake, D.K.
Deposit date:2009-06-05
Release date:2009-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:ATP Hydrolysis in Eg5 Kinesin Involves a Catalytic Two-water Mechanism.
J.Biol.Chem., 285, 2010
3KEN
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BU of 3ken by Molmil
Human Eg5 in complex with S-trityl-L-cysteine
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, MAGNESIUM ION, ...
Authors:Parke, C.L, Wojcik, E.J, Kim, S, Worthylake, D.K.
Deposit date:2009-10-26
Release date:2010-03-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Allosteric drug discrimination is coupled to mechanochemical changes in the kinesin-5 motor core.
J.Biol.Chem., 285, 2010
1HIW
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BU of 1hiw by Molmil
TRIMERIC HIV-1 MATRIX PROTEIN
Descriptor: HIV-1 MATRIX PROTEIN, SULFATE ION
Authors:Hill, C.P, Worthylake, D, Bancroft, D.P, Christensen, A.M, Sundquist, W.I.
Deposit date:1996-02-28
Release date:1996-10-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of the trimeric human immunodeficiency virus type 1 matrix protein: implications for membrane association and assembly.
Proc.Natl.Acad.Sci.USA, 93, 1996
1GLA
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BU of 1gla by Molmil
STRUCTURE OF THE REGULATORY COMPLEX OF ESCHERICHIA COLI IIIGLC WITH GLYCEROL KINASE
Descriptor: GLUCOSE-SPECIFIC PROTEIN IIIGlc, GLYCEROL, GLYCEROL KINASE
Authors:Hurley, J.H, Worthylake, D, Faber, H.R, Meadow, N.D, Roseman, S, Pettigrew, D.W, Remington, S.J.
Deposit date:1992-10-28
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the regulatory complex of Escherichia coli IIIGlc with glycerol kinase.
Science, 259, 1993
1GLB
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BU of 1glb by Molmil
STRUCTURE OF THE REGULATORY COMPLEX OF ESCHERICHIA COLI IIIGLC WITH GLYCEROL KINASE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLUCOSE-SPECIFIC PROTEIN IIIGlc, GLYCEROL, ...
Authors:Hurley, J.H, Worthylake, D, Faber, H.R, Meadow, N.D, Roseman, S, Pettigrew, D.W, Remington, S.J.
Deposit date:1992-10-28
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the regulatory complex of Escherichia coli IIIGlc with glycerol kinase.
Science, 259, 1993
1KZ7
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BU of 1kz7 by Molmil
Crystal Structure of the DH/PH Fragment of Murine Dbs in Complex with the Placental Isoform of Human Cdc42
Descriptor: CDC42 HOMOLOG, GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS
Authors:Rossman, K.L, Worthylake, D.K, Snyder, J.T, Siderovski, D.P, Campbell, S.L, Sondek, J.
Deposit date:2002-02-06
Release date:2002-03-20
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.
EMBO J., 21, 2002
1KZG
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DbsCdc42(Y889F)
Descriptor: CDC42 HOMOLOG, GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS
Authors:Rossman, K.L, Worthylake, D.K, Snyder, J.T, Siderovski, D.P, Campbell, S.L, Sondek, J.
Deposit date:2002-02-06
Release date:2002-03-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.
EMBO J., 21, 2002
1LB1
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Crystal Structure of the Dbl and Pleckstrin homology domains of Dbs in complex with RhoA
Descriptor: Guanine nucleotide exchange factor DBS, Transforming protein RhoA
Authors:Snyder, J.T, Worthylake, D.K, Rossman, K.L, Betts, L, Pruitt, W.M, Siderovski, D.P, Der, C.J, Sondek, J.
Deposit date:2002-04-01
Release date:2002-05-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
Nat.Struct.Biol., 9, 2002

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