4H20

Crystal Structure and Computational Modeling of the Fab Fragment from the Protective anti-Ricin Monoclonal Antibody RAC18

Summary for 4H20

Entry DOI	10.2210/pdb4h20/pdb
Descriptor	Light chain of Fab Fragment from the anti-Ricin Monoclonal Antibody RAC18, Heavy chain of Fab Fragment from the anti-Ricin Monoclonal Antibody RAC18 (3 entities in total)
Functional Keywords	ig, anti ricin antibody fab fragment, ricin a chain, extracellular, bloodstream, immune system
Biological source	Mus musculus More
Total number of polymer chains	2
Total formula weight	47057.61
Authors	Zhao, Z.,Worthylake, D.K.,LeCour Jr., L.F.,Maresh, G.,Pincus, S.H. (deposition date: 2012-09-11, release date: 2012-10-10, Last modification date: 2024-11-20)
Primary citation	Zhao, Z.,Worthylake, D.,Lecour, L.,Maresh, G.A.,Pincus, S.H. Crystal structure and computational modeling of the fab fragment from a protective anti-ricin monoclonal antibody. Plos One, 7:e52613-e52613, 2012 Cited by PubMed Abstract: Many antibody crystal structures have been solved. Structural modeling programs have been developed that utilize this information to predict 3-D structures of an antibody based upon its sequence. Because of the problem of self-reference, the accuracy and utility of these predictions can only be tested when a new structure has not yet been deposited in the Protein Data Bank. PubMed: 23285112 DOI: 10.1371/journal.pone.0052613 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation