3HQD

Human kinesin Eg5 motor domain in complex with AMPPNP and Mg2+

Summary for 3HQD

Entry DOI	10.2210/pdb3hqd/pdb
Related	1ii6 1q0b 1x88 2ieh
Descriptor	Kinesin-like protein KIF11, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PHOSPHATE ION, ... (5 entities in total)
Functional Keywords	kinesin, motor domain, atp hydrolysis, mitosis, spindle protein, atp-binding, cell cycle, cell division, coiled coil, microtubule, motor protein, nucleotide-binding, phosphoprotein, polymorphism
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P52732
Total number of polymer chains	2
Total formula weight	83493.45
Authors	Parke, C.L.,Wojcik, E.J.,Kim, S.,Worthylake, D.K. (deposition date: 2009-06-05, release date: 2009-12-08, Last modification date: 2023-09-06)
Primary citation	Parke, C.L.,Wojcik, E.J.,Kim, S.,Worthylake, D.K. ATP Hydrolysis in Eg5 Kinesin Involves a Catalytic Two-water Mechanism. J.Biol.Chem., 285:5859-5867, 2010 Cited by PubMed: 20018897 DOI: 10.1074/jbc.M109.071233 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.19 Å)

Structure validation