1FOE
CRYSTAL STRUCTURE OF RAC1 IN COMPLEX WITH THE GUANINE NUCLEOTIDE EXCHANGE REGION OF TIAM1
Summary for 1FOE
Entry DOI | 10.2210/pdb1foe/pdb |
NMR Information | BMRB: 5511 |
Descriptor | T-LYMPHOMA INVASION AND METASTASIS INDUCING PROTEIN 1, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE, SULFATE ION, ... (4 entities in total) |
Functional Keywords | dbl homology domain, pleckstrin homology domain, gtpase, guanine nucleotide exchange factor, signaling protein, immune system-signaling protein complex, immune system/signaling protein |
Biological source | Mus musculus (house mouse) More |
Cellular location | Cell junction (By similarity): Q60610 Cell membrane; Lipid-anchor; Cytoplasmic side (By similarity): P63000 |
Total number of polymer chains | 8 |
Total formula weight | 254537.46 |
Authors | Worthylake, D.K.,Rossman, K.L.,Sondek, J. (deposition date: 2000-08-27, release date: 2001-01-17, Last modification date: 2011-07-13) |
Primary citation | Worthylake, D.K.,Rossman, K.L.,Sondek, J. Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1. Nature, 408:682-688, 2000 Cited by PubMed: 11130063DOI: 10.1038/35047014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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