1FOE
CRYSTAL STRUCTURE OF RAC1 IN COMPLEX WITH THE GUANINE NUCLEOTIDE EXCHANGE REGION OF TIAM1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | T-LYMPHOMA INVASION AND METASTASIS INDUCING PROTEIN 1 | polymer | 377 | 43827.5 | 4 | UniProt (Q60610) Pfam (PF00621) | Mus musculus (house mouse) | TIAM1 PROTEIN, T-CELL LYMPHOMA INVASION AND METASTASIS 1 |
| 2 | B, D, F, H (B, D, F, H) | RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE | polymer | 177 | 19710.8 | 4 | UniProt (P63000) Pfam (PF00071) | Homo sapiens (human) | P21-RAC1, RAS-LIKE PROTEIN TC25, RAC1 P21(SMALL) GTP-BINDING PROTEIN |
| 3 | I, J, K, L (B, D, F, H) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | M, N, O, P, Q... (A, B, C, D, E...) | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence modifications
A, C, E, G: 1030 - 1406 (UniProt: Q60610)
| PDB | External Database | Details |
|---|---|---|
| Mse 1031 | Thr 1031 | modified residue |
| Gly 1032 | Thr 1032 | cloning artifact |
| Mse 1063 | Met 1063 | modified residue |
| Mse 1091 | Met 1091 | modified residue |
| Mse 1224 | Met 1224 | modified residue |
| Mse 1234 | Met 1234 | modified residue |
| Mse 1264 | Met 1264 | modified residue |
| Mse 1334 | Met 1334 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 254153.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 384.3 | |
| All* | Total formula weight | 254537.5 |
