5YR0

Structure of Beclin1-UVRAG coiled coil domain complex

Summary for 5YR0

• Entry DOI: 10.2210/pdb5yr0/pdb
• Descriptor: Beclin-1, UV radiation resistance associated protein (3 entities in total)
• Functional Keywords: autophagy regulator, endocytosis
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 2
• Total formula weight: 11589.12

Authors

Pan, X.,Zhao, Y.,He, Y. (deposition date: 2017-11-08, release date: 2018-06-13, Last modification date: 2024-03-27)

• Primary citation: Wu, S.,He, Y.,Qiu, X.,Yang, W.,Liu, W.,Li, X.,Li, Y.,Shen, H.M.,Wang, R.,Yue, Z.,Zhao, Y.; Targeting the potent Beclin 1-UVRAG coiled-coil interaction with designed peptides enhances autophagy and endolysosomal trafficking.; Proc. Natl. Acad. Sci. U.S.A., 115:E5669-E5678, 2018; PubMed: 29866835; DOI: 10.1073/pnas.1721173115

Experimental method

X-RAY DIFFRACTION (1.9 Å)