8CVT

Human 19S-20S proteasome, state SD2

This is a non-PDB format compatible entry.

Summary for 8CVT

• Entry DOI: 10.2210/pdb8cvt/pdb
• EMDB information: 27013 27014 27015 27016 27017 27018 27019
• Descriptor: 26S proteasome regulatory subunit 7, Proteasome subunit alpha type-7, Proteasome subunit alpha type-5, ... (35 entities in total)
• Functional Keywords: proteolysis, protein degradation, complex, inhibitor, mg-132, mg132, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 46
• Total formula weight: 1668000.70

Authors

Zhao, J. (deposition date: 2022-05-18, release date: 2022-11-02)

• Primary citation: Zhao, J.,Makhija, S.,Zhou, C.,Zhang, H.,Wang, Y.,Muralidharan, M.,Huang, B.,Cheng, Y.; Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.; Proc.Natl.Acad.Sci.USA, 119:e2207200119-e2207200119, 2022; PubMed: 35858375; DOI: 10.1073/pnas.2207200119

Experimental method

ELECTRON MICROSCOPY (3 Å)