PDB: 46984 件ウェブページステータス検索Chemie searchBIRD

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4BY1	elongating RNA Polymerase II-Bye1 TLD complex soaked with AMPCPP 分子名称: 5'-D(*AP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP)-3', 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*AP *TP*TP*CP*CP*BRUP*GP*GP*TP*CP*AP*AP*T)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP)-3', ... 著者 Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P. 登録日 2013-07-17 公開日 2013-09-11 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structures of RNA Polymerase II Complexes with Bye1, a Chromatin-Binding Phf3/Dido1 Homologue Proc.Natl.Acad.Sci.USA, 110, 2013
4BXX	Arrested RNA polymerase II-Bye1 complex 分子名称: 5'-D(*AP*GP*CP*TP*AP*GP*CP*TP*TP*AP*CP*CP*TP*GP *GP*TP*GP* BRUP*TP*GP*CP*TP*CP*TP*AP*AP*DC)-3', 5'-D(*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP)-3', 5'-D(*GP*AP*GP*GP*TP*AP*AP*GP*CP*TP*AP*GP*CP*TP)-3', ... 著者 Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P. 登録日 2013-07-16 公開日 2013-09-11 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.28 Å) 主引用文献 Structures of RNA Polymerase II Complexes with Bye1, a Chromatin-Binding Phf3/Dido1 Homologue Proc.Natl.Acad.Sci.USA, 110, 2013
3JCS	2.8 Angstrom cryo-EM structure of the large ribosomal subunit from the eukaryotic parasite Leishmania 分子名称: 26S alpha ribosomal RNA, 26S delta ribosomal RNA, 26S epsilon ribosomal RNA, ... 著者 Shalev-Benami, M, Zhang, Y, Matzov, D, Halfon, Y, Zackay, A, Rozenberg, H, Zimmerman, E, Bashan, A, Jaffe, C.L, Yonath, A, Skiniotis, G. 登録日 2016-01-21 公開日 2016-07-20 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 2.8- angstrom Cryo-EM Structure of the Large Ribosomal Subunit from the Eukaryotic Parasite Leishmania. Cell Rep, 16, 2016
4R67	Human constitutive 20S proteasome in complex with carfilzomib 分子名称: N-{(2S)-2-[(morpholin-4-ylacetyl)amino]-4-phenylbutanoyl}-L-leucyl-N-[(2R,3S,4S)-1,3-dihydroxy-2,6-dimethylheptan-4-yl]-L-phenylalaninamide, Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, ... 著者 Sacchettini, J.C, Harshbarger, W.H. 登録日 2014-08-22 公開日 2015-02-11 最終更新日 2015-02-18 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Crystal Structure of the Human 20S Proteasome in Complex with Carfilzomib. Structure, 23, 2015
6SE6	Class2 : CENP-A nucleosome in complex with CENP-C central region 分子名称: Centromere protein C, DNA (145-MER), Histone H2A type 2-A, ... 著者 Ali-Ahmad, A, Bilokapic, S, Schafer, I.B, Halic, M, Sekulic, N. 登録日 2019-07-29 公開日 2019-08-14 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 CENP-C unwraps the human CENP-A nucleosome through the H2A C-terminal tail. Embo Rep., 20, 2019
6SEE	Class2A : CENP-A nucleosome in complex with CENP-C central region 分子名称: Centromere protein C, DNA (145-MER), Histone H2A type 2-A, ... 著者 Ali-Ahmad, A, Bilokapic, S, Schafer, I.B, Halic, M, Sekulic, N. 登録日 2019-07-29 公開日 2019-08-14 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 CENP-C unwraps the human CENP-A nucleosome through the H2A C-terminal tail. Embo Rep., 20, 2019
6FYX	Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C1) 分子名称: 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ... 著者 Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V. 登録日 2018-03-12 公開日 2018-12-05 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition. Elife, 7, 2018
6FT6	Structure of the Nop53 pre-60S particle bound to the exosome nuclear cofactors 分子名称: 25S ribosomal RNA, 5S ribosomal RNA, 60S ribosomal protein L11-A, ... 著者 Schuller, J.M, Falk, S, Conti, E. 登録日 2018-02-20 公開日 2018-03-28 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structure of the nuclear exosome captured on a maturing preribosome. Science, 360, 2018
5MLU	Crystal structure of the PFV GAG CBS bound to a mononucleosome 分子名称: DNA (145-MER), Histone H2A type 1, Histone H2B, ... 著者 Pye, V.E, Maskell, D.P, Lesbats, P, Cherepanov, P. 登録日 2016-12-07 公開日 2017-05-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for spumavirus GAG tethering to chromatin. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6FQ6	Class 2 : distorted nucleosome 分子名称: DNA (147-MER), Histone H2A, Histone H2B, ... 著者 Bilokapic, S, Halic, M. 登録日 2018-02-13 公開日 2018-04-18 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural rearrangements of the histone octamer translocate DNA. Nat Commun, 9, 2018
4RFQ	Human Methyltransferase-Like 18 分子名称: Histidine protein methyltransferase 1 homolog, S-ADENOSYLMETHIONINE, UNKNOWN ATOM OR ION 著者 Tempel, W, Ravichandran, M, Li, Y, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Hong, B.S, Structural Genomics Consortium (SGC) 登録日 2014-09-26 公開日 2014-10-08 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Human Methyltransferase-Like 18 TO BE PUBLISHED
6FQ5	Class 1 : canonical nucleosome 分子名称: DNA (147-MER), Histone H2A, Histone H2B, ... 著者 Bilokapic, S, Halic, M. 登録日 2018-02-13 公開日 2018-04-18 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural rearrangements of the histone octamer translocate DNA. Nat Commun, 9, 2018
4NE5	Human MHF1-MHF2 complex 分子名称: Centromere protein S, Centromere protein X 著者 Zhao, Q, Saro, D, Sachpatzidis, A, Sung, P, Xiong, Y. 登録日 2013-10-28 公開日 2013-12-25 最終更新日 2014-02-12 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes. Nat Commun, 5, 2014
6FSZ	Structure of the nuclear RNA exosome 分子名称: ATP-dependent RNA helicase DOB1, Exosome complex component CSL4, Exosome complex component MTR3, ... 著者 Schuller, J.M, Falk, S, Conti, E. 登録日 2018-02-20 公開日 2018-03-21 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Structure of the nuclear exosome captured on a maturing preribosome. Science, 360, 2018
4XOB	Crystal structure of a FimH*DsF complex from E.coli K12 with bound heptyl alpha-D-mannopyrannoside 分子名称: FimF, Protein FimH, SULFATE ION, ... 著者 Jakob, R.P, Eras, J, Navarra, G, Ernst, B, Glockshuber, R, Maier, T. 登録日 2015-01-16 公開日 2016-01-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.003 Å) 主引用文献 Catch-bond mechanism of the bacterial adhesin FimH. Nat Commun, 7, 2016
6G0L	Structure of two molecules of the chromatin remodelling enzyme Chd1 bound to a nucleosome 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ... 著者 Sundaramoorthy, R, Owen-hughes, T, Norman, D.G, Hughes, A. 登録日 2018-03-19 公開日 2018-08-22 最終更新日 2018-11-21 実験手法 ELECTRON MICROSCOPY (10 Å) 主引用文献 Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome. Elife, 7, 2018
6FYY	Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C2) 分子名称: 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ... 著者 Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V. 登録日 2018-03-12 公開日 2018-12-05 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.02 Å) 主引用文献 Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition. Elife, 7, 2018
6TCZ	Leishmania tarentolae proteasome 20S subunit complexed with LXE408 分子名称: Proteasome endopeptidase complex, Proteasome subunit alpha type, Proteasome subunit beta, ... 著者 Srinivas, H. 登録日 2019-11-07 公開日 2020-08-26 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Discovery and Characterization of Clinical Candidate LXE408 as a Kinetoplastid-Selective Proteasome Inhibitor for the Treatment of Leishmaniases. J.Med.Chem., 63, 2020
1LWS	Crystal structure of the intein homing endonuclease PI-SceI bound to its recognition sequence 分子名称: CALCIUM ION, ENDONUCLEASE PI-SCEI, PI-SceI DNA recognition region bottom strand, ... 著者 Moure, C.M, Gimble, F.S, Quiocho, F.A. 登録日 2002-06-03 公開日 2002-09-27 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Crystal structure of the intein homing endonuclease PI-SceI bound to its recognition sequence. Nat.Struct.Biol., 9, 2002
6TD5	Leishmania tarentolae proteasome 20S subunit complexed with LXE408 and bortezomib 分子名称: N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, Proteasome endopeptidase complex, Proteasome subunit alpha type, ... 著者 Srinivas, H. 登録日 2019-11-07 公開日 2020-08-26 最終更新日 2020-10-21 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Discovery and Characterization of Clinical Candidate LXE408 as a Kinetoplastid-Selective Proteasome Inhibitor for the Treatment of Leishmaniases. J.Med.Chem., 63, 2020
6TNN	Mini-RNase III (Mini-III) bound to 50S ribosome with precursor 23S rRNA 分子名称: 50S ribosomal protein L10, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Oerum, S, Dendooven, T, Gilet, L, Catala, M, Degut, C, Trinquier, A, Barraud, P, Luisi, B, Condon, C, Tisne, C. 登録日 2019-12-09 公開日 2020-09-30 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.07 Å) 主引用文献 Structures of B. subtilis Maturation RNases Captured on 50S Ribosome with Pre-rRNAs. Mol.Cell, 80, 2020
6TQN	rrn anti-termination complex without S4 分子名称: 30S ribosomal protein S10, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Huang, Y.H, Wahl, M.C, Loll, B, Hilal, T, Said, N. 登録日 2019-12-17 公開日 2020-08-05 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis. Mol.Cell, 79, 2020
6GH5	Cryo-EM structure of bacterial RNA polymerase-sigma54 holoenzyme transcription open complex 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Glyde, R, Ye, F.Z, Zhang, X.D. 登録日 2018-05-04 公開日 2018-07-04 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structures of Bacterial RNA Polymerase Complexes Reveal the Mechanism of DNA Loading and Transcription Initiation. Mol. Cell, 70, 2018
6GTH	Serial Femtosecond Crystallography at Megahertz pulse rates 分子名称: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase 著者 Wiedorn, M, Oberthuer, D, Werner, N, Schubert, R, White, T.A, Mancuso, A, Perbandt, M, Betzel, C, Barty, A, Chapman, H. 登録日 2018-06-18 公開日 2018-10-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Megahertz serial crystallography. Nat Commun, 9, 2018
3LJA	Using Soft X-Rays for a Detailed Picture of Divalent Metal Binding in the Nucleosome 分子名称: 147mer DNA, Histone H2A, Histone H2B 1.1, ... 著者 Wu, B, Davey, C.A. 登録日 2010-01-26 公開日 2010-04-14 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Using soft X-rays for a detailed picture of divalent metal binding in the nucleosome J.Mol.Biol., 398, 2010

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