7PCR
 
 | | Helicobacter pylori RNase J | | Descriptor: | Ribonuclease J | | Authors: | Luisi, B.F, Pei, X.Y. | | Deposit date: | 2021-08-03 | | Release date: | 2022-05-25 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Acetylation regulates the oligomerization state and activity of RNase J, the Helicobacter pylori major ribonuclease.
Nat Commun, 14, 2023
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1NIH
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5NQB
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1R4O
 | | Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA | | Descriptor: | 5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*TP*CP*GP*AP*TP*GP*TP*TP*CP*TP*G)-3', Glucocorticoid receptor, ZINC ION | | Authors: | Luisi, B.F, Xu, W.X, Otwinowski, Z, Freedman, L.P, Yamamoto, K.R, Sigler, P.B. | | Deposit date: | 2003-10-07 | | Release date: | 2003-10-21 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystallographic Analysis of the Interaction of The Glucocorticoid Receptor with DNA
Nature, 352, 1991
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1COH
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1R4R
 | | Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA | | Descriptor: | 5'-D(*CP*TP*GP*AP*GP*AP*AP*CP*AP*TP*CP*AP*TP*GP*TP*TP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*AP*AP*CP*AP*TP*GP*AP*TP*GP*TP*TP*CP*TP*CP*A)-3', Glucocorticoid receptor, ... | | Authors: | Luisi, B.F, Xu, W.X, Otwinowski, Z, Freedman, L.P, Yamamoto, K.R, Sigler, P.B. | | Deposit date: | 2003-10-07 | | Release date: | 2003-10-28 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystallographic Analysis of the Interaction of the Glucocorticoid Receptor with DNA
Nature, 352, 1991
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5NQQ
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1GLU
 | | CRYSTALLOGRAPHIC ANALYSIS OF THE INTERACTION OF THE GLUCOCORTICOID RECEPTOR WITH DNA | | Descriptor: | DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*TP*CP*GP*AP*TP*GP*TP*TP*C P*TP*G)-3'), PROTEIN (GLUCOCORTICOID RECEPTOR), ZINC ION | | Authors: | Luisi, B.F, Xu, W.X, Otwinowski, Z, Freedman, L.P, Yamamoto, K.R, Sigler, P.B. | | Deposit date: | 1992-08-30 | | Release date: | 1994-01-31 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA.
Nature, 352, 1991
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8B0J
 | | CryoEM structure of bacterial RNaseE.RapZ.GlmZ complex central to the control of cell envelope biogenesis | | Descriptor: | GlmZ small RNA, RNase adapter protein RapZ, Ribonuclease E | | Authors: | Islam, M.S, Hardwick, H.W, Chirgadze, D.Y, Luisi, B.F. | | Deposit date: | 2022-09-07 | | Release date: | 2022-10-05 | | Last modified: | 2023-01-25 | | Method: | ELECTRON MICROSCOPY (3.99 Å) | | Cite: | Structure of a bacterial ribonucleoprotein complex central to the control of cell envelope biogenesis.
Embo J., 42, 2023
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8B0I
 | | CryoEM structure of bacterial RapZ.GlmZ complex central to the control of cell envelope biogenesis | | Descriptor: | GlmZ small regulatory RNA, RNase adapter protein RapZ | | Authors: | Islam, M.S, Hardwick, H.W, Chirgadze, D.Y, Luisi, B.F. | | Deposit date: | 2022-09-07 | | Release date: | 2022-10-05 | | Last modified: | 2023-01-25 | | Method: | ELECTRON MICROSCOPY (4.28 Å) | | Cite: | Structure of a bacterial ribonucleoprotein complex central to the control of cell envelope biogenesis.
Embo J., 42, 2023
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7AUA
 | | Cryo-EM structure of human exostosin-like 3 (EXTL3) in complex with UDP | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Exostosin-like 3, MANGANESE (II) ION, ... | | Authors: | Wilson, L.F.L, Dendooven, T, Hardwick, S.W, Chirgadze, D.Y, Luisi, B.F, Logan, D.T, Mani, K, Dupree, P. | | Deposit date: | 2020-11-02 | | Release date: | 2022-05-18 | | Last modified: | 2022-06-15 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis.
Nat Commun, 13, 2022
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7AU2
 | | Cryo-EM structure of human exostosin-like 3 (EXTL3) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Exostosin-like 3, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Wilson, L.F.L, Dendooven, T, Hardwick, S.W, Chirgadze, D.Y, Luisi, B.F, Logan, D.T, Mani, K, Dupree, P. | | Deposit date: | 2020-11-02 | | Release date: | 2022-05-18 | | Last modified: | 2022-06-15 | | Method: | ELECTRON MICROSCOPY (2.43 Å) | | Cite: | The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis.
Nat Commun, 13, 2022
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5A0V
 | | Catalysis and 5' end sensing by ribonuclease RNase J of the metallo- beta-lactamase family | | Descriptor: | 5'-R(*CP*GP*CP*CP*UP*CP)-3', CYTIDINE-5'-MONOPHOSPHATE, RIBONUCLEASE J, ... | | Authors: | Pei, X.Y, Bralley, P, Jones, G.H, Luisi, B.F. | | Deposit date: | 2015-04-23 | | Release date: | 2015-08-19 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Linkage of Catalysis and 5' End Recognition in Ribonuclease Rnase J
Nucleic Acids Res., 43, 2015
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5A0T
 | | Catalysis and 5' end sensing by ribonuclease RNase J of the metallo- beta-lactamase family | | Descriptor: | 5'-R(*CP*GP*CP*CP*UP)-3', DI(HYDROXYETHYL)ETHER, RIBONUCLEASE J, ... | | Authors: | Pei, X.Y, Bralley, P, Jones, G.H, Luisi, B.F. | | Deposit date: | 2015-04-22 | | Release date: | 2015-08-19 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.283 Å) | | Cite: | Linkage of Catalysis and 5' End Recognition in Ribonuclease Rnase J
Nucleic Acids Res., 43, 2015
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5NC5
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7PCF
 | | Human methemoglobin bound to Staphylococcus aureus hemophore IsdB | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, Iron-regulated surface determinant protein B, ... | | Authors: | De Bei, O, Gianquinto, E, Chirgadze, D.Y, Hardwick, S.W, Spyrakis, F, Luisi, B.F, Campanini, B. | | Deposit date: | 2021-08-03 | | Release date: | 2022-04-13 | | Method: | ELECTRON MICROSCOPY (5.82 Å) | | Cite: | Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7PCQ
 | | Human carboxyhemoglobin bound to Staphylococcus aureus hemophore IsdB - 1:1 complex | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, Iron-regulated surface determinant protein B, ... | | Authors: | De Bei, O, Gianquinto, E, Chirgadze, D.Y, Hardwick, S.W, Spyrakis, F, Luisi, B.F, Campanini, B. | | Deposit date: | 2021-08-03 | | Release date: | 2022-04-13 | | Method: | ELECTRON MICROSCOPY (3.62 Å) | | Cite: | Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7PCH
 | | Human carboxyhemoglobin bound to Staphylococcus aureus hemophore IsdB - 1:2 complex | | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, Iron-regulated surface determinant protein B, ... | | Authors: | De Bei, O, Gianquinto, E, Chirgadze, D.Y, Hardwick, S.W, Spyrakis, F, Luisi, B.F, Campanini, B. | | Deposit date: | 2021-08-03 | | Release date: | 2022-04-13 | | Method: | ELECTRON MICROSCOPY (2.89 Å) | | Cite: | Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction.
Proc.Natl.Acad.Sci.USA, 119, 2022
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4UOT
 | | Thermodynamic hyperstability in parametrically designed helical bundles | | Descriptor: | DESIGNED HELICAL BUNDLE 5H2L | | Authors: | Oberdorfer, G, Huang, P, Pei, X.Y, Xu, C, Gonen, T, Nannenga, B, DiMaio, D, Rogers, J, Luisi, B.F, Baker, D. | | Deposit date: | 2014-06-09 | | Release date: | 2014-11-05 | | Last modified: | 2014-11-19 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | High Thermodynamic Stability of Parametrically Designed Helical Bundles
Science, 346, 2014
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4UOS
 | | Thermodynamic hyperstability in parametrically designed helical bundles | | Descriptor: | DESIGNED HELICAL BUNDLE | | Authors: | Oberdorfer, G, Huang, P, Pei, X.Y, Xu, C, Gonen, T, Nannenga, B, DiMaio, D, Rogers, J, Luisi, B.F, Baker, D. | | Deposit date: | 2014-06-09 | | Release date: | 2014-11-05 | | Last modified: | 2016-12-14 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | High Thermodynamic Stability of Parametrically Designed Helical Bundles
Science, 346, 2014
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4OXP
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6G63
 | | RNase E in complex with sRNA RrpA | | Descriptor: | RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), Ribonuclease E, URIDINE-5'-MONOPHOSPHATE, ... | | Authors: | Bandyra, K.B, Luisi, B.F. | | Deposit date: | 2018-03-31 | | Release date: | 2018-10-03 | | Last modified: | 2018-10-31 | | Method: | X-RAY DIFFRACTION (3.95 Å) | | Cite: | Substrate Recognition and Autoinhibition in the Central Ribonuclease RNase E.
Mol. Cell, 72, 2018
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4RMO
 | | Crystal Structure of the CptIN Type III Toxin-Antitoxin System from Eubacterium rectale | | Descriptor: | CALCIUM ION, CptN Toxin, RNA (45-MER) | | Authors: | Rao, F, Voss, J.E, Short, F.L, Luisi, B.F. | | Deposit date: | 2014-10-21 | | Release date: | 2015-09-30 | | Last modified: | 2015-11-18 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Co-evolution of quaternary organization and novel RNA tertiary interactions revealed in the crystal structure of a bacterial protein-RNA toxin-antitoxin system.
Nucleic Acids Res., 43, 2015
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8BVJ
 | | Hfq-Crc-estA translation repression complex | | Descriptor: | Catabolite repression control protein, RNA-binding protein Hfq, estA mRNA | | Authors: | Dendooven, T, Luisi, B.F. | | Deposit date: | 2022-12-04 | | Release date: | 2023-01-25 | | Last modified: | 2023-02-08 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Translational regulation by Hfq-Crc assemblies emerges from polymorphic ribonucleoprotein folding.
Embo J., 42, 2023
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3GCM
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