7PCQ
Human carboxyhemoglobin bound to Staphylococcus aureus hemophore IsdB - 1:1 complex
Summary for 7PCQ
Entry DOI | 10.2210/pdb7pcq/pdb |
EMDB information | 13325 |
Descriptor | Hemoglobin subunit alpha, Hemoglobin subunit beta, Iron-regulated surface determinant protein B, ... (4 entities in total) |
Functional Keywords | iron acquisition, hemophore, hemoglobin, neat domain, metal transport |
Biological source | Staphylococcus aureus subsp. aureus MW2 More |
Total number of polymer chains | 5 |
Total formula weight | 107940.18 |
Authors | De Bei, O.,Gianquinto, E.,Chirgadze, D.Y.,Hardwick, S.W.,Spyrakis, F.,Luisi, B.F.,Campanini, B. (deposition date: 2021-08-03, release date: 2022-04-13) |
Primary citation | De Bei, O.,Marchetti, M.,Ronda, L.,Gianquinto, E.,Lazzarato, L.,Chirgadze, D.Y.,Hardwick, S.W.,Cooper, L.R.,Spyrakis, F.,Luisi, B.F.,Campanini, B.,Bettati, S. Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction. Proc.Natl.Acad.Sci.USA, 119:e2116708119-e2116708119, 2022 Cited by PubMed: 35357971DOI: 10.1073/pnas.2116708119 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.62 Å) |
Structure validation
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