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7PCH

Human carboxyhemoglobin bound to Staphylococcus aureus hemophore IsdB - 1:2 complex

Summary for 7PCH
Entry DOI10.2210/pdb7pch/pdb
EMDB information13320
DescriptorHemoglobin subunit alpha, Hemoglobin subunit beta, Iron-regulated surface determinant protein B, ... (5 entities in total)
Functional Keywordsiron acquisition, hemophore, hemoglobin, neat domain, metal transport
Biological sourceStaphylococcus aureus subsp. aureus MW2
More
Total number of polymer chains6
Total formula weight151333.31
Authors
De Bei, O.,Gianquinto, E.,Chirgadze, D.Y.,Hardwick, S.W.,Spyrakis, F.,Luisi, B.F.,Campanini, B. (deposition date: 2021-08-03, release date: 2022-04-13)
Primary citationDe Bei, O.,Marchetti, M.,Ronda, L.,Gianquinto, E.,Lazzarato, L.,Chirgadze, D.Y.,Hardwick, S.W.,Cooper, L.R.,Spyrakis, F.,Luisi, B.F.,Campanini, B.,Bettati, S.
Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction.
Proc.Natl.Acad.Sci.USA, 119:e2116708119-e2116708119, 2022
Cited by
PubMed: 35357971
DOI: 10.1073/pnas.2116708119
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (2.89 Å)
Structure validation

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