Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C1)

This is a large structure.

Summary for 6FYX

EMDB information4329 4330 4331 4327 4328
DescriptortRNAi, 18S ribosomal RNA, mRNA (31-MER), ... (51 entities in total)
Functional Keywordsribosome, translation, initiation factors, 40s, eif1a, eif3, eif2, eif5, trnai, 48s pic, small ribosome subunit
Biological sourceSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Total number of polymer chains47
Total molecular weight1762329.1
Llacer, J.L.,Hussain, T.,Gordiyenko, Y.,Ramakrishnan, V. (deposition date: 2018-03-12, release date: 2018-12-05, Last modification date: 2019-12-11)
Primary citation
Llacer, J.L.,Hussain, T.,Saini, A.K.,Nanda, J.D.,Kaur, S.,Gordiyenko, Y.,Kumar, R.,Hinnebusch, A.G.,Lorsch, J.R.,Ramakrishnan, V.
Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7:-, 2018
PubMed: 30475211 (PDB entries with the same primary citation)
DOI: 10.7554/eLife.39273
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone6 2.5% 8.7% 0.41MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation reportDownload