Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C2)

This is a large structure.

Summary for 6FYY

EMDB information4327 4329 4330 4331 4328
DescriptortRNAi, 18S ribosomal RNA, mRNA (31-MER), ... (51 entities in total)
Functional Keywordsribosome, translation, initiation factors, 40s, eif1a, eif3, eif2, eif5, trnai, 48s pic, small ribosome subunit
Biological sourceSaccharomyces cerevisiae (Baker's yeast)
Total number of polymer chains47
Total molecular weight1762414.2
Llacer, J.L.,Hussain, T.,Gordiyenko, Y.,Ramakrishnan, V. (deposition date: 2018-03-12, release date: 2018-12-05, Last modification date: 2019-12-11)
Primary citation
Llacer, J.L.,Hussain, T.,Saini, A.K.,Nanda, J.D.,Kaur, S.,Gordiyenko, Y.,Kumar, R.,Hinnebusch, A.G.,Lorsch, J.R.,Ramakrishnan, V.
Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7:-, 2018
PubMed: 30475211 (PDB entries with the same primary citation)
DOI: 10.7554/eLife.39273
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone7 2.7% 10.1% 0.40MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation reportDownload