6FYY

Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C2)

This is a large structure.

Entity

Chain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1tRNAipolymer7624799.11
Saccharomyces cerevisiae
218S ribosomal RNApolymer1798579454.91
GenBank (CR382124.1)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
3mRNA (31-MER)polymer4915345.01
Saccharomyces cerevisiae
A40S ribosomal protein S0polymer25428264.51
UniProt (Q6CN12)
Pfam (PF00318)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
B40S ribosomal protein S1polymer25529013.71
UniProt (Q6CWD0)
Pfam (PF01015)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
CKLLA0F09812ppolymer25927650.01
UniProt (Q6CKL3)
Pfam (PF00333)
Pfam (PF03719)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
DKLLA0D08305ppolymer23726300.51
UniProt (Q6CRK7)
Pfam (PF00189)
Pfam (PF07650)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
E40S ribosomal protein S4polymer26129617.51
UniProt (Q6CWJ2)
Pfam (PF00467)
Pfam (PF00900)
Pfam (PF01479)
Pfam (PF08071)
Pfam (PF16121)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
FKLLA0D10659ppolymer22725386.01
UniProt (Q6CRA3)
Pfam (PF00177)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
G40S ribosomal protein S6polymer23626970.41
UniProt (Q6CM04)
Pfam (PF01092)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
H40S ribosomal protein S7polymer19021735.31
UniProt (Q6CTD6)
Pfam (PF01251)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
I40S ribosomal protein S8polymer20122642.71
UniProt (Q6CMG3)
Pfam (PF01201)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
JKLLA0E23673ppolymer18821587.01
UniProt (Q6CM18)
Pfam (PF00163)
Pfam (PF01479)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
KKLLA0B08173ppolymer10612584.41
UniProt (Q6CVZ5)
Pfam (PF03501)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
LKLLA0A10483ppolymer15617843.91
UniProt (Q6CX80)
Pfam (PF00366)
Pfam (PF16205)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
M40S ribosomal protein S12polymer13414466.41
UniProt (Q6CLU4)
Pfam (PF01248)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
NKLLA0F18040ppolymer15116989.91
UniProt (Q6CJK0)
Pfam (PF00312)
Pfam (PF08069)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
O40S ribosomal protein S14polymer13714530.71
UniProt (P27069)
Pfam (PF00411)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)RP59
PKLLA0F07843ppolymer14215986.81
UniProt (Q6CKV4)
Pfam (PF00203)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
Q40S ribosomal protein S16polymer14315874.51
UniProt (Q875N2)
Pfam (PF00380)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
RKLLA0B01474ppolymer13615722.21
UniProt (Q6CWU3)
Pfam (PF00833)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
SKLLA0B01562ppolymer14617084.61
UniProt (Q6CWT9)
Pfam (PF00416)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
TKLLA0A07194ppolymer14415879.01
UniProt (Q6CXM0)
Pfam (PF01090)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
UKLLA0F25542ppolymer11713337.61
UniProt (Q6CIM1)
Pfam (PF00338)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
V40S ribosomal protein S21polymer879797.91
UniProt (Q6CXT6)
Pfam (PF01249)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
W40S ribosomal protein S22polymer13014645.01
UniProt (Q6CW21)
Pfam (PF00410)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
XKLLA0B11231ppolymer14516047.91
UniProt (F2Z602)
Pfam (PF00164)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
Y40S ribosomal protein S24polymer13515194.51
UniProt (Q6CU44)
Pfam (PF01282)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
ZKLLA0B06182ppolymer10812002.11
UniProt (Q6CW78)
Pfam (PF03297)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
a40S ribosomal protein S26polymer11913540.01
UniProt (Q6CS01)
Pfam (PF01283)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
b40S ribosomal protein S27polymer828884.41
UniProt (Q6CNL2)
Pfam (PF01667)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
c40S ribosomal protein S28polymer677549.81
UniProt (P33285)
Pfam (PF01200)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)S33
d40S ribosomal protein S29polymer566662.61
UniProt (Q6CPG3)
Pfam (PF00253)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
e40S ribosomal protein S30polymer637141.41
UniProt (Q6CUH5)
Pfam (PF04758)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
fUbiquitin-40S ribosomal protein S27apolymer15017111.01
UniProt (P69061)
Pfam (PF00240)
Pfam (PF01599)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
gKLLA0E12277ppolymer32635830.91
UniProt (Q6CNI7)
Pfam (PF00400)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
h60S ribosomal protein L41-Apolymer253354.21
UniProt (P0CX86)
Pfam (PF05162)
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)L47,Large ribosomal subunit protein eL41-A,YL41
iEukaryotic translation initiation factor 1Apolymer15317462.21
UniProt (P38912)
Pfam (PF01176)
Saccharomyces cerevisiae (Baker's yeast)eIF-1A,Eukaryotic translation initiation factor 4C,eIF-4C
jEukaryotic translation initiation factor 2 subunit alphapolymer30434763.71
UniProt (P20459)
Pfam (PF00575)
Pfam (PF07541)
Saccharomyces cerevisiae (Baker's yeast)eIF-2-alpha
kEukaryotic translation initiation factor 2 subunit gammapolymer52757942.71
UniProt (P32481)
Pfam (PF00009)
Pfam (PF03144)
Pfam (PF09173)
Saccharomyces cerevisiae (Baker's yeast)eIF-2-gamma
lEukaryotic translation initiation factor 2 subunit betapolymer28531631.31
UniProt (P09064)
Pfam (PF01873)
Saccharomyces cerevisiae (Baker's yeast)eIF-2-beta
mEukaryotic translation initiation factor 5polymer40545322.01
UniProt (P38431)
Pfam (PF01873)
Pfam (PF02020)
Saccharomyces cerevisiae (Baker's yeast)eIF-5
oEukaryotic translation initiation factor 3 subunit Apolymer964110517.61
UniProt (P38249)
Saccharomyces cerevisiae (Baker's yeast)eIF3a,Eukaryotic translation initiation factor 3 110 kDa subunit homolog,eIF3 p110,Translation initiation factor eIF3,p110 subunit homolog
pEukaryotic translation initiation factor 3 subunit Bpolymer76388241.81
UniProt (P06103)
Pfam (PF00076)
Pfam (PF08662)
Saccharomyces cerevisiae (Baker's yeast)eIF3b,Cell cycle regulation and translation initiation protein,Eukaryotic translation initiation factor 3 90 kDa subunit,eIF3 p90,Translation initiation factor eIF3 p90 subunit
qeIF3c,Eukaryotic translation initiation factor 3 subunit Cpolymer81286539.51
UniProt (P32497)
Pfam (PF01399)
Saccharomyces cerevisiae (Baker's yeast)eIF3c,Eukaryotic translation initiation factor 3 93 kDa subunit,eIF3 p93,Nuclear transport protein NIP1,Translation initiation factor eIF3,p93 subunit
rEukaryotic translation initiation factor 3 subunit Gpolymer27430520.51
UniProt (A6ZZ25)
Pfam (PF00076)
Pfam (PF12353)
Saccharomyces cerevisiae (Baker's yeast)eIF3g,Eukaryotic translation initiation factor 3 RNA-binding subunit,eIF-3 RNA-binding subunit,Translation initiation factor eIF3 p33 subunit homolog,eIF3 p33 homolog
sEukaryotic translation initiation factor 3 subunit Ipolymer34738803.41
UniProt (A6ZMK5)
Pfam (PF00400)
Saccharomyces cerevisiae (Baker's yeast)eIF3i,Eukaryotic translation initiation factor 3 39 kDa subunit homolog,eIF-3 39 kDa subunit homolog
MAGNESIUM IONnon-polymer24.3117
ZINC IONnon-polymer65.45
METHIONINEnon-polymer149.21
PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTERnon-polymer521.21

Sequence viewer

Contents of the asymmetric unit

PolymersNumber of chains47
Total molecular weight1758573.1
Non-Polymers*Number of molecules124
Total molecular weight3841.1
All*Total molecular weight1762414.2
*Water molecules are not included.
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