6GH5

Cryo-EM structure of bacterial RNA polymerase-sigma54 holoenzyme transcription open complex

Summary for 6GH5

Entry DOI	10.2210/pdb6gh5/pdb
EMDB information	0001 4397
Descriptor	DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (7 entities in total)
Functional Keywords	transcription initiation, dna opening, transcription bubble, open complex, transcription
Biological source	Escherichia coli (strain K12) More
Total number of polymer chains	8
Total formula weight	483169.49
Authors	Glyde, R.,Ye, F.Z.,Zhang, X.D. (deposition date: 2018-05-04, release date: 2018-07-04, Last modification date: 2024-05-15)
Primary citation	Glyde, R.,Ye, F.,Jovanovic, M.,Kotta-Loizou, I.,Buck, M.,Zhang, X. Structures of Bacterial RNA Polymerase Complexes Reveal the Mechanism of DNA Loading and Transcription Initiation. Mol. Cell, 70:1111-1120.e3, 2018 Cited by PubMed: 29932903 DOI: 10.1016/j.molcel.2018.05.021 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.4 Å)

Structure validation