Crystal structure of the PFV GAG CBS bound to a mononucleosome

Summary for 5MLU

DescriptorHistone H3.2, Histone H4, Histone H2A type 1, ... (10 entities in total)
Functional Keywordsnucleosome, gag, prototype foamy virus (pfv), complex, protein, dna, dna binding protein
Biological sourceXenopus laevis (African clawed frog)
Cellular locationNucleus P84233 P62799 P06897
Total number of polymer chains11
Total molecular weight177476.78
Pye, V.E.,Maskell, D.P.,Lesbats, P.,Cherepanov, P. (deposition date: 2016-12-07, release date: 2017-05-10, Last modification date: 2017-05-31)
Primary citation
Lesbats, P.,Serrao, E.,Maskell, D.P.,Pye, V.E.,O'Reilly, N.,Lindemann, D.,Engelman, A.N.,Cherepanov, P.
Structural basis for spumavirus GAG tethering to chromatin.
Proc. Natl. Acad. Sci. U.S.A., 114:5509-5514, 2017
PubMed: 28490494 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1621159114
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.252400.2%0.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution