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8EVS
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Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2 and GDP, Structure II
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Zhao, Y, Rai, J, Li, H.
登録日2022-10-20
公開日2023-09-06
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (2.62 Å)
主引用文献Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EYT
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BU of 8eyt by Molmil
30S_delta_ksgA+KsgA complex
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Sun, J, Kinman, L.F, Jahagirdar, D, Ortega, J, Davis, J.H.
登録日2022-10-28
公開日2023-09-06
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献KsgA facilitates ribosomal small subunit maturation by proofreading a key structural lesion.
Nat.Struct.Mol.Biol., 30, 2023
6MUX
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BU of 6mux by Molmil
The structure of the Plasmodium falciparum 20S proteasome in complex with one PA28 activator
分子名称: 20S proteasome alpha-1 subunit, 20S proteasome alpha-2 subunit, 20S proteasome alpha-3 subunit, ...
著者Metcalfe, R.D, Xie, S.C, Hanssen, E, Gillett, D.L, Leis, A.P, Tilley, L, Griffin, M.D.W.
登録日2018-10-23
公開日2019-08-07
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献The structure of the PA28-20S proteasome complex from Plasmodium falciparum and implications for proteostasis.
Nat Microbiol, 4, 2019
8IHT
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BU of 8iht by Molmil
Rpd3S bound to the nucleosome
分子名称: CALCIUM ION, Chromatin modification-related protein EAF3, DNA (164-MER), ...
著者Zhang, Y, Gang, C.
登録日2023-02-23
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献Structural basis for nucleosome binding and catalysis by the yeast Rpd3S/HDAC holoenzyme.
Cell Res., 33, 2023
5JUO
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BU of 5juo by Molmil
Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure I (fully rotated 40S subunit)
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ...
著者Abeyrathne, P, Koh, C.S, Grant, T, Grigorieff, N, Korostelev, A.A.
登録日2016-05-10
公開日2016-10-05
最終更新日2019-11-27
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Elife, 5, 2016
7ER3
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BU of 7er3 by Molmil
Crystal structure of beta-lactoglobulin complexed with chloroquine
分子名称: (4S)-N~4~-(7-chloroquinolin-4-yl)-N~1~,N~1~-diethylpentane-1,4-diamine, Major allergen beta-lactoglobulin
著者Yao, Q, Ma, J, Xing, Y, Zang, J.
登録日2021-05-05
公開日2022-05-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.598 Å)
主引用文献Binding of Chloroquine to Whey Protein Relieves Its Cytotoxicity while Enhancing Its Uptake by Cells.
J.Agric.Food Chem., 69, 2021
5KGF
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BU of 5kgf by Molmil
Structural model of 53BP1 bound to a ubiquitylated and methylated nucleosome, at 4.5 A resolution
分子名称: DNA (145-MER), Histone H2A type 1, Histone H2B type 1-C/E/F/G/I, ...
著者Wilson, M.D, Benlekbir, S, Sicheri, F, Rubinstein, J.L, Durocher, D.
登録日2016-06-13
公開日2016-07-27
最終更新日2020-01-15
実験手法ELECTRON MICROSCOPY (4.54 Å)
主引用文献The structural basis of modified nucleosome recognition by 53BP1.
Nature, 536, 2016
5KOQ
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BU of 5koq by Molmil
Discovery of TAK-272: A Novel, Potent and Orally Active Renin In-hibitor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-~{tert}-butyl-4-(furan-2-ylmethylamino)-~{N}-(2-methylpropyl)-~{N}-[(3~{S})-piperidin-3-yl]pyrimidine-5-carboxamide, DI(HYDROXYETHYL)ETHER, ...
著者Snell, G.P, Behnke, C.A, Okada, K, Hideyuki, O, Sang, B.-C, Lane, W.
登録日2016-07-01
公開日2016-11-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure-based design of a new series of N-(piperidin-3-yl)pyrimidine-5-carboxamides as renin inhibitors.
Bioorg.Med.Chem., 24, 2016
5KOB
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BU of 5kob by Molmil
Crystal structure of a peptide deformylase from Burkholderia xenovorans
分子名称: 1,2-ETHANEDIOL, FE (II) ION, FORMIC ACID, ...
著者SSGCID, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2016-06-30
公開日2016-07-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of a peptide deformylase from Burkholderia xenovorans
to be published
7FDL
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BU of 7fdl by Molmil
Crystal structure of transcription factor WER in complex with EGL3
分子名称: Transcription factor EGL1, Transcription factor WER
著者Luo, Q, Wang, B.
登録日2021-07-17
公開日2022-07-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.897 Å)
主引用文献Structural insights into partner selection for MYB and bHLH transcription factor complexes.
Nat.Plants, 8, 2021
8JLD
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BU of 8jld by Molmil
Cryo-EM structure of the 145 bp human nucleosome containing acetylated H3 tail
分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H.
登録日2023-06-02
公開日2023-10-04
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.48 Å)
主引用文献Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
6NK1
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BU of 6nk1 by Molmil
EphA2 LBD in complex with bA-WLA-YRPKbio peptide
分子名称: ACETATE ION, Ephrin type-A receptor 2, GLYCEROL, ...
著者Lechtenberg, B.C, Pasquale, E.B.
登録日2019-01-04
公開日2019-05-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Engineering nanomolar peptide ligands that differentially modulate EphA2 receptor signaling.
J.Biol.Chem., 294, 2019
7EVO
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BU of 7evo by Molmil
The cryo-EM structure of the human 17S U2 snRNP
分子名称: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, RNA helicase, ...
著者Zhang, X, Zhan, X, Shi, Y.
登録日2021-05-21
公開日2022-08-03
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structural insights into branch site proofreading by human spliceosome.
Nat.Struct.Mol.Biol., 2024
4N5C
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BU of 4n5c by Molmil
Crystal structure of Ypp1
分子名称: Cargo-transport protein YPP1
著者Wu, X, Chi, R.J, Baskin, J.M, Lucast, L, Burd, C.G, De Camilli, P, Reinisch, K.M.
登録日2013-10-09
公開日2014-01-22
最終更新日2014-03-19
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structural insights into assembly and regulation of the plasma membrane phosphatidylinositol 4-kinase complex.
Dev.Cell, 28, 2014
5QU6
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BU of 5qu6 by Molmil
Crystal Structure of swapped human Nck SH3.1 domain, 1.8A, triclinic
分子名称: Cytoplasmic protein NCK1
著者Rudolph, M.G.
登録日2019-12-13
公開日2020-02-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.816 Å)
主引用文献Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
1ESY
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BU of 1esy by Molmil
NMR STRUCTURE OF STEM LOOP SL2 OF THE HIV-1 PSI RNA PACKAGING SIGNAL REVEALS A NOVEL A-U-A BASE-TRIPLE PLATFORM
分子名称: RNA (5'-R(P*GP*GP*CP*GP*AP*CP*UP*GP*GP*UP*GP*AP*GP*UP*AP*CP*GP*CP*C)-3')
著者Amarasinghe, G.K, De Guzman, R.N, Turner, R.B, Summers, M.F.
登録日2000-04-11
公開日2000-05-31
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR structure of stem-loop SL2 of the HIV-1 psi RNA packaging signal reveals a novel A-U-A base-triple platform.
J.Mol.Biol., 299, 2000
8JDI
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BU of 8jdi by Molmil
Crystal structure of Cas7-AcrIF25 complex
分子名称: AcrIF25, CRISPR-associated protein Csy3
著者Yang, J, Wang, J, Wang, Y.
登録日2023-05-14
公開日2024-05-29
最終更新日2024-07-24
実験手法X-RAY DIFFRACTION (3.372 Å)
主引用文献An anti-CRISPR that pulls apart a CRISPR-Cas complex.
Nature, 2024
6O9K
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BU of 6o9k by Molmil
70S initiation complex
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Frank, J, Gonzalez Jr, R.L, kaledhonkar, S, Fu, Z, Caban, K, Li, W, Chen, B, Sun, M.
登録日2019-03-14
公開日2019-05-29
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Late steps in bacterial translation initiation visualized using time-resolved cryo-EM.
Nature, 570, 2019
8G6W
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BU of 8g6w by Molmil
Structure of WT E.coli 70S ribosome complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site ortho-aminobenzoic acid charged NH-tRNAPhe
分子名称: 16S rRNA, 2-AMINO-BENZAMIDE, 23S rRNA, ...
著者Majumdar, C, Cate, J.H.D.
登録日2023-02-16
公開日2023-04-05
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.02 Å)
主引用文献Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome.
Acs Cent.Sci., 9, 2023
8G6X
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BU of 8g6x by Molmil
Structure of WT E.coli ribosome 50S subunit with complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site meta-aminobenzoic acid charged NH-tRNAPhe
分子名称: 23S rRNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), 3-aminobenzamide, ...
著者Majumdar, C, Cate, J.H.D.
登録日2023-02-16
公開日2023-03-22
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.31 Å)
主引用文献Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome.
Acs Cent.Sci., 9, 2023
8G6Y
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BU of 8g6y by Molmil
Structure of WT E.coli ribosome 50S subunit with complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site 3-aminopyridine-4-carboxylic acid charged NH-tRNAPhe
分子名称: 23S rRNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), 3-aminopyridine-4-carboxamide, ...
著者Majumdar, C, Cate, J.H.D.
登録日2023-02-16
公開日2023-04-05
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.09 Å)
主引用文献Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome.
Acs Cent.Sci., 9, 2023
8GRM
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BU of 8grm by Molmil
Cryo-EM structure of PRC1 bound to H2AK119-UbcH5b-Ub nucleosome
分子名称: COMMD3 protein, DNA (144-MER), DNA (145-MER), ...
著者Ai, H.S, Zebin, T, Zhihend, D, Jiakun, T, Liying, Z, Jia-Bin, L, Man, P, Liu, L.
登録日2022-09-02
公開日2023-04-12
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献Synthetic E2-Ub-nucleosome conjugates for studying nucleosome ubiquitination.
Chem, 2023
8OIN
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BU of 8oin by Molmil
55S mammalian mitochondrial ribosome with mtRF1 and P-site tRNA
分子名称: 12S rRNA, 16S rRNA, 28S ribosomal protein S15, ...
著者Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N.
登録日2023-03-23
公開日2023-06-14
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
Science, 380, 2023
7DCT
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BU of 7dct by Molmil
Crystal structure of HSF1 DNA-binding domain in complex with 3-site HSE DNA (24 bp)
分子名称: DNA (5'-D(*AP*CP*TP*CP*GP*CP*GP*AP*AP*TP*AP*TP*TP*CP*TP*AP*GP*AP*AP*CP*GP*CP*AP*C)-3'), DNA (5'-D(*TP*GP*TP*GP*CP*GP*TP*TP*CP*TP*AP*GP*AP*AP*TP*AP*TP*TP*CP*GP*CP*GP*AP*G)-3'), Heat shock factor protein 1, ...
著者Feng, N, Liu, W.
登録日2020-10-27
公開日2021-07-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structures of heat shock factor trimers bound to DNA.
Iscience, 24, 2021
1N32
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Structure of the Thermus thermophilus 30S ribosomal subunit bound to codon and near-cognate transfer RNA anticodon stem-loop mismatched at the first codon position at the a site with paromomycin
分子名称: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
著者Ogle, J.M, Murphy IV, F.V, Tarry, M.J, Ramakrishnan, V.
登録日2002-10-25
公開日2002-11-29
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Selection of tRNA by the Ribosome Requires a Transition from an Open to a Closed Form
Cell(Cambridge,Mass.), 111, 2002

223532

件を2024-08-07に公開中

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