PDB: 30476 件ウェブページステータス検索Chemie searchBIRD

---

5ZVP	Aspergillus fumigatus Rho1 F25N 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho GTPase Rho1, ... 著者 Wei, W.F, Van Aalten, D.M.F. 登録日 2018-05-12 公開日 2019-05-15 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Aspergillus fumigateurs Rho1 F25N To Be Published
4Z4B	2-Pyridyl Hoechst - a New Generation DNA-Binding Radioprotector 分子名称: 5-(4-methylpiperazin-1-yl)-2'-(pyridin-2-yl)-1H,1'H-2,5'-bibenzimidazole, DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*G)-3'), MAGNESIUM ION 著者 Wee, J.-Y, Dobson, R.C.J, White, J.M. 登録日 2015-04-01 公開日 2016-05-04 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.9652 Å) 主引用文献 2-Pyridyl Hoechst - a New Generation DNA-Binding Radioprotector To Be Published
5ZUT	Crystal Structure of Yeast PCNA in Complex with N24 Peptide 分子名称: N24, Proliferating cell nuclear antigen 著者 Cheng, X.Y, Kuang, X.L, Zhou, Y, Xia, X.M, SU, Z.D. 登録日 2018-05-08 公開日 2018-05-30 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.82 Å) 主引用文献 Crystal Structure of Yeast PCNA in Complex with N24 Peptide To Be Published
5ZW9	Crystal structure of Pyridoxal kinase (PdxK) from Salmonella typhimurium 分子名称: 1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DI(HYDROXYETHYL)ETHER, ... 著者 Deka, G, Benazir, J.F, Kalyani, J.N, Savithri, H.S, Murthy, M.R.N. 登録日 2018-05-14 公開日 2019-05-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural and functional studies on Salmonella typhimurium pyridoxal kinase: the first structural evidence for the formation of Schiff base with the substrate. Febs J., 286, 2019
5ZWT	Crystal structure of the S37A mutant of apo-acyl carrier protein from Leishmania major 分子名称: Acyl carrier protein 著者 Sharma, B, Arya, R, Kundu, S, Makde, R.D. 登録日 2018-05-16 公開日 2019-01-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A conformational switch from a closed apo- to an open holo-form equips the acyl carrier protein for acyl chain accommodation. Biochim Biophys Acta Proteins Proteom, 1867, 2018
4Z9M	Crystal structure of human sarcomeric mitochondrial creatine kinase 分子名称: ADENOSINE-5'-DIPHOSPHATE, Creatine kinase S-type, mitochondrial, ... 著者 Rabeh, W.M, Tempel, W, Nedyalkova, L, Landry, R, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2015-04-10 公開日 2015-04-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of human sarcomeric mitochondrial creatine kinase To Be Published
4ZOK	Methylsulfonyl-containing inhibitor bound in the substrate capture site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD) 分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 4-methyl-2-{[2-methyl-6-(methylsulfonyl)phenyl]amino}benzoic acid, Anthranilate phosphoribosyltransferase, ... 著者 Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC) 登録日 2015-05-06 公開日 2016-05-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD). To be Published
5ZZB	LokiProfilin2/Rabbit Actin Complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Robinson, R.C, Akil, C. 登録日 2018-05-31 公開日 2018-10-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Genomes of Asgard archaea encode profilins that regulate actin. Nature, 562, 2018
4ZCW	Structure of Human Enolase 2 in complex with SF2312 分子名称: Gamma-enolase, MAGNESIUM ION, [(3S,5S)-1,5-dihydroxy-2-oxopyrrolidin-3-yl]phosphonic acid 著者 Leonard, P.G, Maxwell, D, Czako, B, Muller, F.L. 登録日 2015-04-16 公開日 2016-07-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.992 Å) 主引用文献 SF2312 is a natural phosphonate inhibitor of enolase. Nat.Chem.Biol., 12, 2016
4ZDC	Yeast enoyl-CoA isomerase complexed with octanoyl-CoA 分子名称: 3,2-trans-enoyl-CoA isomerase, GLYCEROL, OCTANOYL-COENZYME A, ... 著者 Onwukwe, G.U, Koski, M.K, Wierenga, R.K. 登録日 2015-04-17 公開日 2015-11-11 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Structures of yeast peroxisomal Delta (3), Delta (2)-enoyl-CoA isomerase complexed with acyl-CoA substrate analogues: the importance of hydrogen-bond networks for the reactivity of the catalytic base and the oxyanion hole. Acta Crystallogr.,Sect.D, 71, 2015
4ZE2	Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) Y140H mutant complexed with itraconazole 分子名称: 2-[(2R)-butan-2-yl]-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE 著者 Sagatova, A, Keniya, M.V, Wilson, R, Monk, B.C, Tyndall, J.D.A. 登録日 2015-04-20 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14 alpha-demethylase. Sci Rep, 6, 2016
5ZWS	Crystal structure of apo-acyl carrier protein from Leishmania major 分子名称: Acyl carrier protein 著者 Arya, R, Sharma, B, Makde, R.D, Kundu, S. 登録日 2018-05-16 公開日 2019-01-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A conformational switch from a closed apo- to an open holo-form equips the acyl carrier protein for acyl chain accommodation. Biochim Biophys Acta Proteins Proteom, 1867, 2018
5ZYJ	Crystal structure of CERT START domain in complex with compound E16A 分子名称: 2-[4-[4-pentyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol, GLYCEROL, LIPID-TRANSFER PROTEIN CERT 著者 Suzuki, M, Nakao, N, Ueno, M, Sakai, S, Egawa, D, Hanzawa, H, Kawasaki, S, Kumagai, K, Kobayashi, S, Hanada, K. 登録日 2018-05-25 公開日 2019-02-27 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT Commun Chem, 2019
5WSA	Pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate and allosteric activator Glucose 6-Phosphate 分子名称: 6-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, OXALATE ION, ... 著者 Zhong, W, Cai, Q, El Sahili, A, Lescar, J, Dedon, P.C. 登録日 2016-12-06 公開日 2017-11-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Allosteric pyruvate kinase-based "logic gate" synergistically senses energy and sugar levels in Mycobacterium tuberculosis. Nat Commun, 8, 2017
4Z7G	Crystal structure of human IRE1 cytoplasmic kinase-RNase region - apo 分子名称: SODIUM ION, Serine/threonine-protein kinase/endoribonuclease IRE1 著者 Bayliss, R, Joshi, A. 登録日 2015-04-07 公開日 2015-05-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Molecular mechanisms of human IRE1 activation through dimerization and ligand binding. Oncotarget, 6, 2015
5WPB	Crystal structure of fragment 3-(3-(pyridin-2-ylmethoxy)quinoxalin-2-yl)propanoic acid bound in the ubiquitin binding pocket of the HDAC6 zinc-finger domain 分子名称: 3-{3-[(pyridin-2-yl)methoxy]quinoxalin-2-yl}propanoic acid, Histone deacetylase 6, UNKNOWN ATOM OR ION, ... 著者 Harding, R.J, Tempel, W, Ferreira de Freitas, R, Franzoni, I, Ravichandran, M, Lautens, M, Santhakumar, V, Schapira, M, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) 登録日 2017-08-04 公開日 2017-08-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Small Molecule Antagonists of the Interaction between the Histone Deacetylase 6 Zinc-Finger Domain and Ubiquitin. J. Med. Chem., 60, 2017
4Z8J	Crystal structure of the SNX27 PDZ domain bound to the C-terminal PTHR PDZ binding motif 分子名称: C-terminal PDZ binding motif from parathyroid hormone receptor (PTHR), Sorting nexin-27 著者 Clairfeuille, T, Pavlos, N, Collins, B.M. 登録日 2015-04-09 公開日 2016-02-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (0.95 Å) 主引用文献 Role of SNX27-retromer in PTHR trafficking To Be Published
5WPK	Structure of the class II 3-hydroxy-3-methylglutaryl-CoA reductase from Streptococcus pneumoniae bound to HMG-CoA and in a partially closed conformation 分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, 3-hydroxy-3-methylglutaryl coenzyme A reductase, ... 著者 Miller, B.R, Kung, Y. 登録日 2017-08-04 公開日 2018-04-25 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Features and Domain Movements Controlling Substrate Binding and Cofactor Specificity in Class II HMG-CoA Reductase. Biochemistry, 57, 2018
4ZCS	Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase in complex with CDP-choline 分子名称: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Choline-phosphate cytidylyltransferase, [2-CYTIDYLATE-O'-PHOSPHONYLOXYL]-ETHYL-TRIMETHYL-AMMONIUM 著者 Guca, E, Hoh, F, Guichou, J.-F, Cerdan, R. 登録日 2015-04-16 公開日 2016-08-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural determinants of the catalytic mechanism of Plasmodium CCT, a key enzyme of malaria lipid biosynthesis. Sci Rep, 8, 2018
4ZNX	Crystal structure of the Fyn-SH3 domain in complex with the high affinity peptide APP12 分子名称: APP12, Tyrosine-protein kinase Fyn 著者 Camara-Artigas, A. 登録日 2015-05-05 公開日 2016-06-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The role of water molecules in the binding of class I and II peptides to the SH3 domain of the Fyn tyrosine kinase. Acta Crystallogr.,Sect.F, 72, 2016
5WUC	Structural basis for conductance through TRIC cation channels 分子名称: SODIUM ION, Uncharacterized protein 著者 Su, M, Gao, F, Mao, Y, Li, D.L, Guo, Y.Z, Wang, X.H, Bruni, R, Kloss, B, Hendrickson, W.A, Chen, Y.H, New York Consortium on Membrane Protein Structure (NYCOMPS) 登録日 2016-12-17 公開日 2017-07-12 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural basis for conductance through TRIC cation channels. Nat Commun, 8, 2017
4ZQ0	crystal structure of Giardia 14-3-3 in complex with the phosphopeptide A8Ap 分子名称: 14-3-3 protein, A8Ap phosphopeptide, PHOSPHATE ION 著者 Fiorillo, A, Ilari, A. 登録日 2015-05-08 公開日 2016-03-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Molecular Dynamics Simulations and Structural Analysis of Giardia duodenalis 14-3-3 Protein-Protein Interactions. J.Chem.Inf.Model., 55, 2015
4ZGH	Structure of Sugar Binding Protein Pneumolysin 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GOLD (I) CYANIDE ION, ... 著者 Parker, M.W, Feil, S.C, Morton, C. 登録日 2015-04-23 公開日 2016-03-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of Streptococcus pneumoniae pneumolysin provides key insights into early steps of pore formation. Sci Rep, 5, 2015
4ZHE	Crystal structure of the SeMet substituted Topless related protein 2 (TPR2) N-terminal domain (1-209) from rice 分子名称: ASPR2 protein 著者 Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K. 登録日 2015-04-24 公開日 2015-08-05 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors. Sci Adv, 1, 2015
5WV7	Crystal structure of d(CCGGGGTACCCCGG)2 at 1.4A resolution 分子名称: DNA (5'-D(*CP*CP*GP*GP*GP*GP*TP*AP*CP*CP*CP*CP*GP*G)-3') 著者 Karthik, S, Thirugnanasambandam, A, Mandal, P.K, Gautham, N. 登録日 2016-12-22 公開日 2017-05-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.406 Å) 主引用文献 Crystal structure of d(CCGGGGTACCCCGG)2 at 1.4 angstrom resolution. Acta Crystallogr F Struct Biol Commun, 73, 2017

<395396397398399400401402403404405406407408409410>